{"id":"W4410546762","doi":"10.1038/s41537-025-00610-4","title":"Body fluid biomarkers and psychosis risk in The Accelerating Medicines Partnership® Schizophrenia Program: design considerations","year":2025,"lang":"en","type":"article","venue":"Schizophrenia","topic":"Fibromyalgia and Chronic Fatigue Syndrome Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas College","funders":"National Institutes of Health; Wellcome Trust; National Institute of Mental Health; U.S. Department of Health and Human Services","keywords":"Psychosis; Schizophrenia (object-oriented programming); General partnership; Medicine; Psychiatry; Psychology; Business; Finance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0946343,0.001052023,0.001486313,0.001007245,0.002050923,0.004445354,0.003593179,0.002899393,0.0135453],"category_scores_gemma":[0.06214992,0.0009322339,0.002166942,0.001550611,0.001637004,0.002120539,0.003978617,0.002844637,0.001998033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003909593,"about_ca_system_score_gemma":0.01920022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01582347,"about_ca_topic_score_gemma":0.03043314,"domain_scores_codex":[0.9253429,0.06614588,0.001748656,0.001349623,0.004135116,0.001277776],"domain_scores_gemma":[0.9579364,0.02062605,0.003527948,0.00399403,0.008659905,0.005255659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.03865198,0.006371848,0.166991,0.004670045,0.001856996,0.0005834156,0.002066542,0.005927223,0.004049583,0.02377929,0.1400987,0.6049534],"study_design_scores_gemma":[0.02520856,0.05973881,0.2820711,0.009487614,0.00485229,0.001496998,0.00497445,0.02369641,0.01748567,0.06194095,0.5082466,0.000800645],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.190767,0.01477568,0.127184,0.3949389,0.009174864,0.1605961,0.03246057,0.002442479,0.06766035],"genre_scores_gemma":[0.3020693,0.008605761,0.3738168,0.05388194,0.002954623,0.2325247,0.004934879,0.0005005634,0.02071149],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.0946343,"threshold_uncertainty_score":0.50048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04423985498453267,"score_gpt":0.3441027202128477,"score_spread":0.299862865228315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}