{"id":"W4410565377","doi":"10.1111/myc.70069","title":"Efficacy and Safety of Efinaconazole 10% Topical Solution for Treatment of Onychomycosis in Older Adults: A Post Hoc Analysis of Two Phase 3 Randomised Trials","year":2025,"lang":"en","type":"article","venue":"Mycoses","topic":"Nail Diseases and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mediprobe Research (Canada); University of Toronto","funders":"Bausch Health; Ortho Dermatologics","keywords":"Medicine; Post-hoc analysis; Adverse effect; Dermatology; Clinical endpoint; Population; Cure rate; Clinical trial; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000163049,0.0001255818,0.001241767,0.0003563599,0.00001979817,0.000002700312,0.00002904901,0.00004891846,0.0001264603],"category_scores_gemma":[0.000383098,0.00008964067,0.0004329913,0.0003691211,0.00004703966,0.00002366398,0.00001091034,0.00001277684,2.690477e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007103518,"about_ca_system_score_gemma":0.00008325478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003522584,"about_ca_topic_score_gemma":0.00007860438,"domain_scores_codex":[0.9988057,0.0000877609,0.000691223,0.000193906,0.0001040653,0.0001173288],"domain_scores_gemma":[0.9985229,0.0008974904,0.0002130034,0.0001894815,0.0001231457,0.00005394537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4903109,0.0207109,0.06160591,0.0007607916,0.009889096,0.00001147961,0.0007189485,0.00002118063,0.009666337,0.0002553282,0.0001155174,0.4059336],"study_design_scores_gemma":[0.608652,0.004290658,0.345761,0.000632922,0.01659548,5.903622e-7,0.0001483244,0.001094903,0.02242345,0.0000409538,0.0002564618,0.0001033198],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993736,0.003449359,0.000233317,0.0001647439,0.00002474906,0.001750677,0.0005315653,0.00000614515,0.0001034802],"genre_scores_gemma":[0.9983455,0.000710252,0.0003603743,0.00002169385,0.00001247252,0.000126305,0.0002706929,0.000005032761,0.0001476978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4058303,"threshold_uncertainty_score":0.3655441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02418979928987349,"score_gpt":0.3724089059654865,"score_spread":0.3482191066756131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}