{"id":"W4410565377","doi":"10.1111/myc.70069","title":"Efficacy and Safety of Efinaconazole 10% Topical Solution for Treatment of Onychomycosis in Older Adults: A Post Hoc Analysis of Two Phase 3 Randomised Trials","year":2025,"lang":"en","type":"article","venue":"Mycoses","topic":"Nail Diseases and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mediprobe Research (Canada); University of Toronto","funders":"Bausch Health; Ortho Dermatologics","keywords":"Medicine; Post-hoc analysis; Adverse effect; Dermatology; Clinical endpoint; Population; Cure rate; Clinical trial; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00929678,0.002278974,0.005590569,0.0005709433,0.0005027818,0.00195836,0.001072382,0.002086377,0.005720111],"category_scores_gemma":[0.007387886,0.0007787131,0.007622299,0.0006409251,0.001258838,0.001430217,0.0006887728,0.002510969,0.0006645151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001331747,"about_ca_system_score_gemma":0.001817933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000961943,"about_ca_topic_score_gemma":0.0022955,"domain_scores_codex":[0.9950299,0.003341416,0.0004479708,0.0005219941,0.0002960248,0.0003625557],"domain_scores_gemma":[0.9938798,0.002549609,0.001909816,0.0004911639,0.0005317564,0.0006378589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9824758,0.001541293,0.0005230862,0.001300552,0.005859191,0.00002657134,0.00004999904,0.0002502156,0.001827404,0.00003669328,0.0003365372,0.005772598],"study_design_scores_gemma":[0.8861371,0.09888001,0.004753442,0.0001479844,0.007965021,0.00004595802,0.00004331056,0.0004824314,0.0006184496,0.0001381952,0.0007520002,0.00003606853],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9578695,0.02138185,0.001964873,0.0006918411,0.0009472362,0.01242579,0.002437771,0.0001805349,0.002100711],"genre_scores_gemma":[0.9756943,0.005793178,0.002586962,0.0008376256,0.0004840622,0.0111291,0.001319175,0.00004815392,0.002107423],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00929678,"threshold_uncertainty_score":0.04916662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02418979928987349,"score_gpt":0.3724089059654865,"score_spread":0.3482191066756131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}