{"id":"W4410578393","doi":"10.1021/acsomega.5c01382","title":"Anti-Trypanosoma cruzi Effect of Fatty Acids from Porcelia macrocarpa Is Related to Interactions of Cell Membranes at Different Microdomains as Assessed Using Langmuir Monolayers","year":2025,"lang":"en","type":"article","venue":"ACS Omega","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Trypanosoma cruzi; Membrane; Monolayer; Langmuir; Chemistry; Cell; Biochemistry; Organic chemistry; Computer science; Adsorption; Parasite hosting","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007880616,0.0003706345,0.0001796501,0.0001648795,0.00008722225,0.0001415897,0.0001142431,0.0001688518,0.001122805],"category_scores_gemma":[0.0001009544,0.0001163162,0.0001814302,0.0001244055,0.0001294536,0.0001073193,0.0001412009,0.0002789635,0.0002366143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009358299,"about_ca_system_score_gemma":0.00008083872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005759858,"about_ca_topic_score_gemma":0.0006327996,"domain_scores_codex":[0.9999341,0.00001621379,0.000004900803,0.00001290857,0.00001162612,0.00002022286],"domain_scores_gemma":[0.9999259,0.00001899603,0.00002186355,0.000005052569,0.00001187669,0.00001636292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001535018,0.00001193234,0.0000649957,0.0000251478,0.000004397516,0.00002196886,0.000005875224,0.00001570357,0.9991346,0.000006258039,0.00001214709,0.0005435187],"study_design_scores_gemma":[0.00001503696,0.000679248,0.005307208,0.000007823292,0.00002314708,0.0001319902,0.00002355963,0.0001667531,0.9923225,0.000008361209,0.001310901,0.000003511327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995742,0.001373281,0.0008355419,0.00009460007,0.00001754303,0.00002027843,0.0002136404,0.00003386859,0.001669224],"genre_scores_gemma":[0.9947732,0.001209964,0.001414183,0.0001505629,0.00001081683,0.00001760765,0.0009015662,0.00002320086,0.001498967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001122805,"threshold_uncertainty_score":0.003756166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01329722848785714,"score_gpt":0.3202505221383727,"score_spread":0.3069532936505156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}