{"id":"W4410580051","doi":"10.1139/cjm-2023-0223","title":"Disruption of MAPK signalling and amino acid biosynthesis underlies the antifungal biocontrol mechanism of <i>Coniochaeta velutina</i> against <i>Colletotrichum gloeosporioides</i>: a transcriptome and metabolome analysis","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Metabolome; Biology; Transcriptome; Metabolomics; Secondary metabolism; Biochemistry; Biosynthesis; De novo transcriptome assembly; Metabolic pathway; Colletotrichum; Metabolite; Metabolism; Microbiology; Botany; Gene expression; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007440416,0.0004281095,0.0002261351,0.0001788853,0.0001705557,0.0003404391,0.0001321401,0.0002235824,0.000380303],"category_scores_gemma":[0.00006837056,0.000117109,0.0003129465,0.0001506158,0.0001645069,0.000219477,0.0002138148,0.0003088697,0.0001334394],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000310867,"about_ca_system_score_gemma":0.0002063711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00111808,"about_ca_topic_score_gemma":0.001352663,"domain_scores_codex":[0.9999119,0.000008135316,0.000005447851,0.00002732436,0.00001727021,0.00002982773],"domain_scores_gemma":[0.999936,0.000006017429,0.00002822157,0.000004451283,0.0000104747,0.0000147458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003184207,0.000005262363,0.0004183137,0.00001398562,0.000002530681,0.00002088965,0.000006653494,0.00002645862,0.9991038,0.00001183611,0.000007062838,0.0003514671],"study_design_scores_gemma":[0.00001799933,0.0002516201,0.1499896,0.0000134394,0.00004716876,0.0004261218,0.0001555055,0.002140067,0.8450675,0.0001323147,0.001746952,0.00001178467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967312,0.0007736298,0.001403743,0.00006352924,0.000005402359,0.0000177122,0.0003543623,0.0000530248,0.000597591],"genre_scores_gemma":[0.9975684,0.0004437666,0.0006798632,0.00004317216,0.000003560501,0.00001786468,0.0005035882,0.000009903049,0.0007297687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00111808,"threshold_uncertainty_score":0.002255499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007952955935893256,"score_gpt":0.2117570544868306,"score_spread":0.2038040985509374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}