{"id":"W4410586923","doi":"10.1016/j.annonc.2025.05.528","title":"Localised rectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up","year":2025,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Colorectal Cancer Surgical Treatments","field":"Medicine","cited_by":129,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Cilag; Genentech; Foundation Medicine; Sierra Oncology; INCLIVA Instituto de Investigación Sanitaria; Nordic Pharma Group; Daiichi Sankyo Europe; Gilead Sciences; Servier; Deutsche Krebshilfe; European Society for Medical Oncology; FibroGen; Astellas Pharma; Aptitude Health; Natera; Seagen; Actuate Therapeutics; F-star Therapeutics; Boston Scientific Corporation; Ribon Therapeutics; BeiGene; Sanofi; Les Laboratories Pierre Fabre; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb; Amgen","keywords":"Medicine; Guideline; Colorectal cancer; Clinical Practice; Cancer; General surgery; Oncology; Intensive care medicine; Internal medicine; Family medicine; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004690271,0.001210991,0.001849852,0.003798333,0.001240178,0.001614414,0.002597329,0.005258814,0.005595391],"category_scores_gemma":[0.02232799,0.0008916415,0.002892486,0.003130931,0.0007509259,0.001370165,0.002731631,0.00550638,0.005804351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004181366,"about_ca_system_score_gemma":0.01134373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03707337,"about_ca_topic_score_gemma":0.09408067,"domain_scores_codex":[0.994673,0.001631262,0.001756476,0.0002385345,0.001181789,0.0005190102],"domain_scores_gemma":[0.9857625,0.002690407,0.002590312,0.0002719084,0.007420179,0.001264689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001148218,0.0002078545,0.01229701,0.002104772,0.0001811693,0.0005817057,0.0003295807,0.002132801,0.0006778981,0.001780687,0.8323477,0.147244],"study_design_scores_gemma":[0.0003337363,0.0002303322,0.05476906,0.02295743,0.0005550062,0.003776639,0.0007468841,0.002707467,0.0007512485,0.005753277,0.9072636,0.0001553631],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.01488272,0.1804685,0.05069402,0.49107,0.01513937,0.007356572,0.03781159,0.002218388,0.2003588],"genre_scores_gemma":[0.105231,0.2141234,0.3110987,0.1679888,0.01030114,0.01854352,0.09481128,0.001208338,0.07669389],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.03707337,"threshold_uncertainty_score":0.07371515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1677152634567655,"score_gpt":0.5441843588012119,"score_spread":0.3764690953444464,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}