{"id":"W4410601000","doi":"10.1007/978-1-0716-4474-4_7","title":"Evaluation and Quantification of Blood-Brain Barrier Permeability in a Photothrombotic Juvenile Rodent Stroke Model Using In Vivo MRI and Histology","year":2025,"lang":"en","type":"book-chapter","venue":"Neuromethods","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"Rodent model; Histology; Rodent; In vivo; Juvenile; Blood–brain barrier; Permeability (electromagnetism); Medicine; Pathology; Biology; Neuroscience; Internal medicine; Central nervous system; Membrane; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002660364,0.0005288823,0.0002356988,0.0009411846,0.0001633689,0.0004943275,0.0004860237,0.0006083258,0.007000775],"category_scores_gemma":[0.0001111376,0.0002962516,0.0002227018,0.0004595779,0.0002322269,0.0007407399,0.0001712896,0.0007653477,0.002414925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003199736,"about_ca_system_score_gemma":0.0002911596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001103371,"about_ca_topic_score_gemma":0.003385123,"domain_scores_codex":[0.9999244,0.000005433443,0.000005410681,0.00001710424,0.00003819517,0.00000950191],"domain_scores_gemma":[0.9999136,0.00002210836,0.00001778506,0.000009163945,0.00002780666,0.000009652747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009980639,0.0001224896,0.0002282659,0.0004253837,0.00001421836,0.0003766156,0.00006059212,0.0005554392,0.928729,0.004921111,0.00462287,0.05984437],"study_design_scores_gemma":[0.00002881124,0.0007857356,0.00701956,0.0003222648,0.00009621201,0.004379546,0.000111215,0.005932427,0.8665761,0.003688521,0.1110017,0.00005788682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2135534,0.0614091,0.5082263,0.002929043,0.001753057,0.001160712,0.006398162,0.0061294,0.1984408],"genre_scores_gemma":[0.15455,0.05796259,0.3836222,0.001054639,0.0002441215,0.000693379,0.003353521,0.0009753772,0.3975441],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007000775,"threshold_uncertainty_score":0.02341992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06714501107607984,"score_gpt":0.3574056075461153,"score_spread":0.2902605964700355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}