{"id":"W4410608796","doi":"10.1016/j.tcb.2025.04.006","title":"Translational control of leukemic metabolism and disease progression","year":2025,"lang":"en","type":"review","venue":"Trends in Cell Biology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Jewish General Hospital","funders":"Cole Foundation; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Leukemia and Lymphoma Society of Canada","keywords":"Biology; Disease; Metabolism; Computational biology; Cell biology; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002982107,0.0002899474,0.001849691,0.001019182,0.000020302,0.000003124635,0.0001607729,0.0004423316,0.0001624854],"category_scores_gemma":[0.0001195899,0.0001988839,0.0002785783,0.0005210258,0.0002654435,0.00001720605,0.00006076822,0.0005849157,0.000005451779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001001,"about_ca_system_score_gemma":0.001435198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001318031,"about_ca_topic_score_gemma":0.000002060625,"domain_scores_codex":[0.9981668,0.0003484811,0.0006050243,0.000454714,0.000128141,0.0002968288],"domain_scores_gemma":[0.9987674,0.0005174328,0.0001757633,0.0003069243,0.0000455376,0.000186949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001964589,0.00008185975,0.0002681808,0.01166965,0.00008539347,0.00002848244,0.000013832,2.352312e-7,0.00003362463,0.00042924,0.0002467128,0.9869463],"study_design_scores_gemma":[0.003859241,0.0001173701,0.0006285522,0.005939428,0.001414787,0.00001368262,0.000002376129,0.00007139339,0.000007400406,0.0002588894,0.9874816,0.0002052857],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004656758,0.9945886,0.00003460025,0.0002307138,0.00009037086,0.0005547487,0.0003204897,0.00001718506,0.004116782],"genre_scores_gemma":[0.00200466,0.9946319,0.0002827708,0.00005045139,0.000101047,0.0001499299,0.0009901531,0.00002122481,0.001767819],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9872349,"threshold_uncertainty_score":0.8110249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0373523133793419,"score_gpt":0.394772141043127,"score_spread":0.3574198276637851,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}