{"id":"W4410695756","doi":"10.1101/2025.05.18.654733","title":"Parallel adaptation and admixture drive the evolution of virulence in the grapevine downy mildew pathogen","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Horticultural and Viticultural Research","field":"Agricultural and Biological Sciences","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Agriculture and Agri-Food Canada; HORIZON EUROPE Framework Programme; Institut Carnot Santé Animale; Pécsi Tudományegyetem; Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement; Agence Nationale de la Recherche; European Commission","keywords":"Plasmopara viticola; Biology; Virulence; Downy mildew; Genetics; Locus (genetics); Effector; Oomycete; Population; Introgression; Pathogen; Gene; Botany","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003476499,0.0002627932,0.0002783394,0.0006894295,0.0002496509,0.0004355745,0.000234629,0.0002993225,0.0008431484],"category_scores_gemma":[0.0003235759,0.0001969426,0.0001924325,0.0002429374,0.0002239822,0.0001748387,0.0005714369,0.0005793907,0.0001726492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002842498,"about_ca_system_score_gemma":0.00009597163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000487952,"about_ca_topic_score_gemma":0.0008446042,"domain_scores_codex":[0.9997497,0.00004760874,0.00001367058,0.000103703,0.00003752788,0.00004769818],"domain_scores_gemma":[0.9997942,0.00005922092,0.00003925719,0.00003405068,0.00002393586,0.0000493616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001774476,0.00008036114,0.04554373,0.00002056995,0.00005273586,0.0001791823,0.0001651055,0.0003278771,0.9483996,0.0001975065,0.00003007881,0.004825814],"study_design_scores_gemma":[0.00002947928,0.0004702268,0.9581214,0.00001139497,0.00006946,0.000965582,0.0003539598,0.003926954,0.03435733,0.0003862702,0.001286406,0.00002141665],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990314,0.00007504072,0.0006012522,0.00000921434,0.000001858686,0.00000447601,0.00004268248,0.00000762645,0.0002264318],"genre_scores_gemma":[0.9990901,0.0000502303,0.0003399067,0.00001410413,0.000002793034,0.000005028233,0.0001588658,0.000009730088,0.0003292655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008431484,"threshold_uncertainty_score":0.002820551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02340184963655968,"score_gpt":0.2337374130521467,"score_spread":0.2103355634155871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}