{"id":"W4410715588","doi":"10.3899/jrheum.2025-0390.pv014","title":"PRISTANE-INDUCED LUPUS MICE PRESENT INCREASED MEGAKARYOCYTE COUNTS ALONGSIDE OTHER HISTOPATHOLOGICAL FEATURES IN THE SPLENIC TISSUE","year":2025,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Systemic lupus erythematosus; Megakaryocyte; Pristane; Pathology; Spleen; Connective tissue disease; Lupus erythematosus; Autoimmune disease; Histopathology; Immunology; Antibody; Haematopoiesis; Disease; Stem cell; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001972437,0.0006439228,0.0005433068,0.001143483,0.0002631299,0.0003097134,0.0002172758,0.0005068156,0.005266625],"category_scores_gemma":[0.00009038772,0.0002427317,0.0003372766,0.0003030075,0.0003419955,0.0003250033,0.0002999782,0.0009948238,0.0008685598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001904395,"about_ca_system_score_gemma":0.0001531348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002087869,"about_ca_topic_score_gemma":0.0004866644,"domain_scores_codex":[0.9997067,0.00003065174,0.00003201229,0.00007744696,0.00009319418,0.00005988028],"domain_scores_gemma":[0.9996387,0.00002624829,0.0001293418,0.00002657209,0.00002883341,0.0001503099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009634076,0.0003140831,0.000979192,0.0000989069,0.0000103896,0.0001544401,0.00003163221,0.0000310153,0.9951226,0.00005099289,0.00008965968,0.002153628],"study_design_scores_gemma":[0.0002301077,0.0125886,0.03958267,0.00005067867,0.00008233439,0.002325297,0.0001888192,0.000464774,0.9392766,0.0001707275,0.005008631,0.0000308255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899279,0.00221292,0.002607428,0.000153044,0.00006406099,0.0001401671,0.001442321,0.000235445,0.003216697],"genre_scores_gemma":[0.9745267,0.001982496,0.005484374,0.0001579444,0.00004952385,0.0003407169,0.001865726,0.00005819496,0.0155344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005266625,"threshold_uncertainty_score":0.01761866,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01061965865821548,"score_gpt":0.2492090207279744,"score_spread":0.2385893620697589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}