{"id":"W4410715736","doi":"10.3899/jrheum.2025-0390.o029","title":"RESET SLE: CLINICAL TRIAL EVALUATING CABA-201, A FULLY HUMAN, AUTOLOGOUS 4-1BB ANTI-CD19 CAR T CELL THERAPY IN NONRENAL SLE AND LUPUS NEPHRITIS","year":2025,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Lupus nephritis; CD19; Reset (finance); Internal medicine; Immunology; Antibody","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001195608,0.0007963033,0.001061327,0.0002471725,0.000326251,0.001143378,0.0007054305,0.001118798,0.009354047],"category_scores_gemma":[0.0007879024,0.0002936955,0.00093724,0.0002017361,0.0006856099,0.0007378574,0.0003926354,0.002278829,0.001413473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005817334,"about_ca_system_score_gemma":0.001076127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005249155,"about_ca_topic_score_gemma":0.001647983,"domain_scores_codex":[0.9996785,0.0001444915,0.0000188622,0.00005636151,0.00003366896,0.00006814926],"domain_scores_gemma":[0.9994036,0.00009944443,0.0001071941,0.00004583363,0.00002937095,0.0003144182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8546137,0.01663395,0.004214955,0.002030092,0.001155836,0.0002859842,0.0002260661,0.001537947,0.02844905,0.0009734885,0.008734278,0.08114474],"study_design_scores_gemma":[0.7258411,0.2529457,0.007938146,0.000139228,0.000554237,0.000395549,0.00006707569,0.0009217368,0.002810523,0.0003770146,0.007973545,0.00003626179],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9759267,0.007260491,0.0007616556,0.0009246732,0.0003204735,0.003022595,0.003299929,0.0003753714,0.008108152],"genre_scores_gemma":[0.9818287,0.001778003,0.001468793,0.001659749,0.0002491603,0.002853223,0.003775365,0.00003839407,0.006348703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009354047,"threshold_uncertainty_score":0.03129244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08434236423360857,"score_gpt":0.4347614480405972,"score_spread":0.3504190838069887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}