{"id":"W4410715790","doi":"10.3899/jrheum.2025-0390.pv306","title":"ECULIZUMAB IN THE MANAGEMENT OF CATASTROPHIC ANTIPHOSPHOLIPID SYNDROME WITH MULTIORGAN INVOLVEMENT: A CASE REPORT","year":2025,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Peripheral Neuropathies and Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Eculizumab; Catastrophic antiphospholipid syndrome; Multiorgan failure; Antiphospholipid syndrome; Intensive care medicine; Immunology; Thrombosis; Surgery; Antibody; Complement system","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004692817,0.001988029,0.00148533,0.00320252,0.002425219,0.002215795,0.001263503,0.006219297,0.002145764],"category_scores_gemma":[0.00203143,0.001233061,0.001271298,0.001531888,0.001298556,0.002528625,0.00159108,0.003403586,0.0006344265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001189149,"about_ca_system_score_gemma":0.0008918212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001218742,"about_ca_topic_score_gemma":0.001547725,"domain_scores_codex":[0.9992625,0.0001244275,0.00009125534,0.0001330013,0.0001196535,0.0002691832],"domain_scores_gemma":[0.9988952,0.0003054157,0.0003071683,0.00008451454,0.00005399468,0.0003536578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00001239858,0.00001916083,0.001351514,0.00002013059,0.000005790117,0.997216,0.00005174208,0.00003491628,0.000212219,0.000110059,0.0001861398,0.0007799141],"study_design_scores_gemma":[0.000009758379,0.00002350896,0.001004546,0.00001636467,0.000008879463,0.9979497,0.00005976404,0.0001719745,0.000156007,0.00008890042,0.0005051139,0.000005518029],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9060668,0.0453056,0.009466929,0.01072118,0.001043154,0.0004580628,0.0003019641,0.0004168409,0.02621943],"genre_scores_gemma":[0.9878243,0.0051256,0.002146618,0.001347685,0.001554321,0.00004714459,0.00009472527,0.00002633147,0.001833385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006219297,"threshold_uncertainty_score":0.008627892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009084180096678178,"score_gpt":0.2517498447210469,"score_spread":0.2426656646243688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}