{"id":"W4410715883","doi":"10.3899/jrheum.2025-0390.o053","title":"COMPARATIVE SAFETY OF COMMON IMMUNOSUPPRESSANTS IN SLE: A CLINICAL TRIAL EMULATION ON INFECTION RISK WITH ADJUSTMENT FOR GLUCOCORTICOID DOSE","year":2025,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Glucocorticoid; Emulation; Clinical trial; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1008922,0.002130764,0.003871507,0.001344157,0.0004565809,0.001943544,0.001783371,0.00358008,0.008221069],"category_scores_gemma":[0.09124989,0.000719364,0.01102216,0.001225621,0.001819957,0.0031105,0.002060839,0.003339009,0.0009230641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00102239,"about_ca_system_score_gemma":0.001189106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000197175,"about_ca_topic_score_gemma":0.0003134153,"domain_scores_codex":[0.8742414,0.1148978,0.004523344,0.002784212,0.002306896,0.001246361],"domain_scores_gemma":[0.8900985,0.07688575,0.01873552,0.009334236,0.002822288,0.002123822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.920413,0.002803474,0.01188609,0.002031619,0.01716426,0.0001053143,0.0002411632,0.002589787,0.001833763,0.001344087,0.002246719,0.03734072],"study_design_scores_gemma":[0.5437939,0.3213409,0.06495803,0.001015807,0.02577308,0.0002515096,0.00020728,0.02523067,0.004407221,0.004301356,0.008514372,0.0002058308],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9122342,0.01145264,0.0277669,0.002601995,0.001596007,0.03056109,0.004145004,0.0004449835,0.009197246],"genre_scores_gemma":[0.9511232,0.001359372,0.01910728,0.001327239,0.0006742006,0.02270658,0.001428089,0.00007093915,0.00220299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1008922,"threshold_uncertainty_score":0.5335753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04901096936858849,"score_gpt":0.3834901858778517,"score_spread":0.3344792165092632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}