{"id":"W4410759486","doi":"10.1002/jev2.70093","title":"CD24 Regulates the Formation of Ectosomes in B Lymphocytes","year":2025,"lang":"en","type":"article","venue":"Journal of Extracellular Vesicles","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Terry Fox Research Institute; Beatrice Hunter Cancer Research Institute","keywords":"Cell biology; PI3K/AKT/mTOR pathway; Chemistry; CD24; Flow cytometry; Protein kinase B; Sphingomyelin; Signal transduction; Biology; Stem cell; Molecular biology; Biochemistry; Membrane; Cancer stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001090344,0.0002279472,0.0001788915,0.0002979741,0.0002241378,0.0005827936,0.000114492,0.0002988532,0.001913435],"category_scores_gemma":[0.0001206962,0.0001264532,0.0003181815,0.0001203299,0.0001701316,0.0002673342,0.0003312676,0.0004717667,0.0008031253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004003583,"about_ca_system_score_gemma":0.0001177911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002898208,"about_ca_topic_score_gemma":0.0003441997,"domain_scores_codex":[0.999815,0.0000341597,0.00001579001,0.00003686337,0.00004653768,0.00005178079],"domain_scores_gemma":[0.999904,0.000009977172,0.00002777877,0.000006640116,0.00001586157,0.00003566205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007110114,0.00001120218,0.0002881549,0.00002172928,0.000003120078,0.0000682526,0.0000104599,0.00003070237,0.9984655,0.000125932,0.00003619241,0.0008676472],"study_design_scores_gemma":[0.00001872038,0.0001345933,0.01774601,0.00001179876,0.00001565824,0.0003918844,0.00008083415,0.00074946,0.9758006,0.0001267313,0.004917273,0.000006477406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905306,0.004328171,0.002041077,0.0001171075,0.00003943219,0.00002424408,0.0003045054,0.00008212098,0.002532834],"genre_scores_gemma":[0.9938971,0.0009317664,0.001081295,0.00003909816,0.00001087163,0.00002786107,0.0003287647,0.00002616776,0.003657023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001913435,"threshold_uncertainty_score":0.006401062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006694444787015747,"score_gpt":0.2435444165271248,"score_spread":0.236849971740109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}