{"id":"W4410772614","doi":"10.1002/cncy.70023","title":"The diagnostic challenges of medullary thyroid carcinoma: A practical guide for cytopathologists","year":2025,"lang":"en","type":"review","venue":"Cancer Cytopathology","topic":"Thyroid Cancer Diagnosis and Treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Thyroid carcinoma; Medullary thyroid cancer; Thyroid; Radiology; Fine-needle aspiration; Thyroid cancer; Medullary cavity; Thyroid nodules; Pathology; Biopsy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007211689,0.0006858874,0.003289628,0.0002141713,0.000186807,0.00001795895,0.0003830387,0.0006642332,0.00001851973],"category_scores_gemma":[0.00349671,0.0004216877,0.001080007,0.0002656769,0.0005304637,0.00003719552,0.000236635,0.0005465226,0.00001185705],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006136266,"about_ca_system_score_gemma":0.003313274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003178524,"about_ca_topic_score_gemma":0.0001181595,"domain_scores_codex":[0.9963889,0.0004259073,0.001227627,0.0009791615,0.0002706516,0.0007077827],"domain_scores_gemma":[0.9892625,0.00819194,0.0007826223,0.0012489,0.0003429813,0.0001711035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001431374,0.0003751749,0.0002885609,0.03064751,0.0004022929,0.001012648,0.00007874806,3.970977e-7,0.000002805542,0.009663278,0.01460934,0.9427761],"study_design_scores_gemma":[0.001366123,0.001185392,0.000909607,0.01033962,0.006335605,0.00110721,0.00008418968,6.093866e-7,0.00002868791,0.0002816698,0.9780356,0.0003257266],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002642521,0.9886524,0.00006612758,0.004014498,0.001373478,0.003607163,0.0004997053,0.00006032371,0.001699886],"genre_scores_gemma":[0.0003172856,0.9857533,0.0005989356,0.0001977305,0.000660381,0.01149486,0.0001067519,0.00008507221,0.000785691],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9634262,"threshold_uncertainty_score":0.9998235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07761293523654657,"score_gpt":0.4239042750793523,"score_spread":0.3462913398428057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}