{"id":"W4410774925","doi":"10.1016/j.mcpro.2025.101000","title":"A Method for Comparing Proteins Measured in Serum and Plasma by Olink Proximity Extension Assay","year":2025,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Pennsylvania Department of Health; National Institute of Child Health and Human Development; Alex's Lemonade Stand Foundation for Childhood Cancer","keywords":"Extension (predicate logic); Blood proteins; Computational biology; Chemistry; Computer science; Biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007697945,0.003387704,0.001433512,0.006642956,0.001716471,0.002604446,0.001911173,0.002146703,0.003449689],"category_scores_gemma":[0.01829421,0.001578068,0.001939854,0.004074065,0.002090735,0.00238723,0.003117337,0.004061572,0.004600508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00106652,"about_ca_system_score_gemma":0.001894184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007962377,"about_ca_topic_score_gemma":0.00130974,"domain_scores_codex":[0.9823439,0.005173148,0.001581567,0.004937829,0.005319408,0.0006440872],"domain_scores_gemma":[0.9874027,0.005248188,0.00300573,0.001609704,0.002240784,0.0004927756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008051038,0.0002697022,0.004944244,0.001078804,0.0002568515,0.0002625306,0.0006345109,0.001017079,0.9332972,0.002930041,0.001736124,0.05276776],"study_design_scores_gemma":[0.0001020863,0.0009096006,0.01056803,0.0002822206,0.0003052894,0.001187645,0.0002747098,0.01351001,0.9342361,0.002939199,0.03544001,0.0002450928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.05412048,0.004556549,0.9269772,0.0003973021,0.0006188968,0.001105311,0.002108085,0.005764185,0.004352017],"genre_scores_gemma":[0.0840399,0.003631127,0.896157,0.0005040952,0.0001363231,0.004781181,0.003317364,0.0007071021,0.00672589],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.007697945,"threshold_uncertainty_score":0.0407111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307107026348409,"score_gpt":0.2764976852488539,"score_spread":0.2634266149853698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}