{"id":"W4410792230","doi":"10.1002/art.43263","title":"Impact of Interleukin‐1 Blockade on the Development of Macrophage Activation Syndrome in Still Disease: Incidence and Diagnostic Validity of the <scp>EULAR</scp> / <scp>ACR</scp> / <scp>PRINTO</scp> 2016 <scp>MAS</scp> Classification Criteria","year":2025,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"ZonMw; Swedish Orphan Biovitrum; Arthritis Society; Dutch Arthritis Society; Pfizer","keywords":"Medicine; Blockade; Immunology; Disease; Cytokine release syndrome; Incidence (geometry); Neuroscience; Immune system; Internal medicine; T cell; Psychology; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001699867,0.000156899,0.000383979,0.0003774713,0.0001465669,0.0006641799,0.0002443891,0.000319601,0.0009379176],"category_scores_gemma":[0.005559705,0.0001192599,0.0004247259,0.0005149326,0.0002970687,0.0004613547,0.0003121581,0.0002951647,0.0001120451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003953652,"about_ca_system_score_gemma":0.0004592352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002487606,"about_ca_topic_score_gemma":0.002883397,"domain_scores_codex":[0.9982281,0.0006787846,0.0002532964,0.000278969,0.0003666699,0.0001941804],"domain_scores_gemma":[0.9937969,0.00216353,0.003078096,0.0001951427,0.0004067712,0.0003595387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000593139,0.00002952368,0.996055,0.00002096044,0.00007338496,0.00008744217,0.00003536762,0.00004408373,0.0003903589,0.00001172948,0.00003656984,0.002622362],"study_design_scores_gemma":[0.00002225891,0.0004040918,0.9985273,0.000012751,0.00006155398,0.0004230351,0.00008292509,0.0002211977,0.0001128864,0.00000820902,0.0001213005,0.000002548323],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985282,0.0009542339,0.00004438025,0.00002798443,0.000004670222,0.000006264879,0.0001155246,8.971137e-7,0.0003177758],"genre_scores_gemma":[0.9996693,0.0001092834,0.00003381207,0.00001010188,0.000006210435,0.000003214627,0.0001362882,6.893294e-7,0.00003112143],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002487606,"threshold_uncertainty_score":0.008989871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02063569519143352,"score_gpt":0.300469659000932,"score_spread":0.2798339638094985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}