{"id":"W4410795580","doi":"10.1200/jco.2025.43.16_suppl.7515","title":"Minimal residual disease (MRD) negativity (neg) in patients (pts) with relapsed or refractory multiple myeloma (RRMM) treated with belantamab mafodotin plus pomalidomide and dexamethasone (BPd) vs pomalidomide, bortezomib, and dexamethasone (PVd): Analysis from the DREAMM-8 trial.","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Pomalidomide; Medicine; Dexamethasone; Oncology; Bortezomib; Multiple myeloma; Internal medicine; Lenalidomide; Refractory (planetary science)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002132521,0.0004496314,0.001151679,0.000205307,0.0001889062,0.0006403939,0.0005631695,0.0006078537,0.001974272],"category_scores_gemma":[0.001541656,0.0003353015,0.001536415,0.0003459778,0.0005888832,0.0004490343,0.000430227,0.001200106,0.0002826748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008374885,"about_ca_system_score_gemma":0.000721417,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008264939,"about_ca_topic_score_gemma":0.002834032,"domain_scores_codex":[0.9992341,0.0004409264,0.00007987583,0.0001270561,0.00006231543,0.00005576503],"domain_scores_gemma":[0.9992303,0.0002026331,0.000276183,0.00005224825,0.00002708019,0.0002115818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9183432,0.003700702,0.0280442,0.001158696,0.003623961,0.00008569096,0.0001574987,0.001115741,0.004401435,0.000164996,0.001518527,0.03768539],"study_design_scores_gemma":[0.6194037,0.2492697,0.1158477,0.0002390193,0.006214458,0.0004309591,0.0001601895,0.001737725,0.001914524,0.0005403212,0.004190493,0.00005116558],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945687,0.003334095,0.0001828974,0.0002552609,0.00004967489,0.0004038619,0.000678537,0.00001121066,0.0005156954],"genre_scores_gemma":[0.9967272,0.0008333377,0.0003326114,0.0002772478,0.00006283545,0.0004652288,0.0008743925,0.000003484049,0.0004235326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002132521,"threshold_uncertainty_score":0.01127797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06137079237664723,"score_gpt":0.395330562548901,"score_spread":0.3339597701722538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}