{"id":"W4410803435","doi":"10.1200/jco.2025.43.16_suppl.tps3644","title":"Colon adjuvant chemotherapy based on evaluation of residual disease (CIRCULATE-NORTH AMERICA): NRG-GI008.","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Colorectal and Anal Carcinomas","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natera","keywords":"Medicine; Adjuvant; Adjuvant chemotherapy; Chemotherapy; Oncology; Disease; Internal medicine; Colorectal cancer; Cancer; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003157833,0.0001301462,0.001209352,0.0002118528,0.00003326808,0.000004060383,0.000135655,0.000177221,0.0002441173],"category_scores_gemma":[0.005081401,0.00009180229,0.0005523623,0.0003044615,0.0002406035,0.00004017757,0.00002325962,0.0006099601,0.000006602093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002177625,"about_ca_system_score_gemma":0.004400279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001243288,"about_ca_topic_score_gemma":0.00003404629,"domain_scores_codex":[0.9963997,0.0007314897,0.001733315,0.0001946065,0.0007750312,0.0001658273],"domain_scores_gemma":[0.9956876,0.001573638,0.001225285,0.0002140844,0.0009838081,0.0003155625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.04084408,0.004917094,0.3918302,0.0001045314,0.0003954597,0.0003661949,0.00006218832,0.001945947,0.0003881801,0.00007280068,0.00848165,0.5505917],"study_design_scores_gemma":[0.01160626,0.01188123,0.946332,0.0001955544,0.001009018,0.000008804536,0.00004420033,0.01087145,0.0001093688,0.000437275,0.01742887,0.00007594896],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9782379,0.0004639151,0.00009399012,0.01652118,0.0006437519,0.0002953449,0.000006572255,0.000007458326,0.00372988],"genre_scores_gemma":[0.9921396,0.0001402525,0.0002646879,0.006736185,0.0004868675,0.000005079812,0.00001067731,0.000009712014,0.000206907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5545018,"threshold_uncertainty_score":0.7805907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1288700032918076,"score_gpt":0.4832084056807142,"score_spread":0.3543384023889066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}