{"id":"W4410809328","doi":"10.1200/jco.2025.43.16_suppl.tps5131","title":"Darolutamide plus androgen deprivation therapy (ADT) in patients with high-risk biochemical recurrence (BCR) of prostate cancer: A phase 3, randomized, double-blind, placebo-controlled study (ARASTEP).","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cégep de Lévis; McGill University","funders":"","keywords":"Medicine; Androgen deprivation therapy; Prostate cancer; Placebo; Oncology; Internal medicine; Biochemical recurrence; Cancer; Urology; Prostatectomy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001686896,0.001460079,0.002021811,0.0004992801,0.0004127179,0.0008047256,0.0009239003,0.001695265,0.008764789],"category_scores_gemma":[0.001154413,0.0005912745,0.001664986,0.0004966527,0.0008358968,0.0008187707,0.0003657741,0.002235655,0.001141524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004853936,"about_ca_system_score_gemma":0.001690902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005166595,"about_ca_topic_score_gemma":0.001832768,"domain_scores_codex":[0.9995549,0.0002151679,0.00003922077,0.0000720633,0.00004717273,0.00007141112],"domain_scores_gemma":[0.9993179,0.0001410976,0.000161005,0.00004855695,0.00005930685,0.0002720964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9545879,0.0159482,0.0008904196,0.001679939,0.0007818393,0.00007577034,0.00006514896,0.0002032916,0.005935808,0.0001113221,0.001172326,0.01854802],"study_design_scores_gemma":[0.9431535,0.05388991,0.001614823,0.00003341809,0.0001988976,0.00003610702,0.00001214683,0.00009571985,0.0002814992,0.00006191323,0.000612931,0.000009174627],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9446759,0.008484328,0.001234006,0.001187693,0.0006767224,0.03628542,0.004321425,0.0002725131,0.002861965],"genre_scores_gemma":[0.9558124,0.005275274,0.003278942,0.00256773,0.0006992748,0.02498689,0.002551071,0.00003698941,0.004791504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008764789,"threshold_uncertainty_score":0.02932107,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06389345534634007,"score_gpt":0.4574562585545091,"score_spread":0.3935628032081691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}