{"id":"W4410812209","doi":"10.2139/ssrn.5251640","title":"Evaluating the Role of Thrombopoietin Receptor Agonists in the Treatment of Acquired Amegakaryocytic Thrombocytopenia: A Case Report and Review of the Literature","year":2025,"lang":"en","type":"preprint","venue":"SSRN Electronic Journal","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Thrombopoietin; Thrombopoietin receptor; Romiplostim; Agonist; Receptor; Medicine; Pharmacology; Internal medicine; Biology; Haematopoiesis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004347339,0.0009220313,0.001237912,0.002664678,0.0006941123,0.002012479,0.001090916,0.003908661,0.001790156],"category_scores_gemma":[0.001751817,0.0004295972,0.0009843671,0.002044524,0.0009827188,0.002152963,0.0004957325,0.001486092,0.0008133639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005644654,"about_ca_system_score_gemma":0.0007191175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006614759,"about_ca_topic_score_gemma":0.000714434,"domain_scores_codex":[0.9995159,0.00007713302,0.0001513539,0.00007298073,0.0001095861,0.00007308381],"domain_scores_gemma":[0.9990319,0.0005622035,0.0002075935,0.00005528807,0.00007517048,0.00006786386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001022555,0.00007447771,0.00646218,0.0009830988,0.00007567669,0.9502456,0.0001873212,0.0001453851,0.003382793,0.0004585482,0.00136711,0.03651559],"study_design_scores_gemma":[0.00001629097,0.00006703157,0.003073234,0.0003225196,0.0001676832,0.9848692,0.0002626618,0.0001914789,0.001391502,0.0004064189,0.009213397,0.00001857364],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1775452,0.7967541,0.003775385,0.004756776,0.0008918704,0.0001128969,0.0002278822,0.0001122725,0.01582356],"genre_scores_gemma":[0.5579283,0.4250867,0.004853711,0.003600218,0.004791779,0.00004439757,0.0003720962,0.00004401478,0.003278829],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003908661,"threshold_uncertainty_score":0.005988717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02122078659320448,"score_gpt":0.3450335784702518,"score_spread":0.3238127918770474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}