{"id":"W4410814984","doi":"10.1200/jco.2025.43.16_suppl.tps4202","title":"Telisotuzumab adizutecan (ABBV-400; Temab-A) in combination with fluorouracil, leucovorin, and budigalimab in locally advanced/metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma (a/m GEA).","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Gastric Cancer Management and Outcomes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"AbbVie","keywords":"Medicine; Gastroesophageal Junction; Esophageal adenocarcinoma; Fluorouracil; Adenocarcinoma; Gastroenterology; Internal medicine; Metastatic adenocarcinoma; Stomach; Surgery; Chemotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009180068,0.0007230958,0.001125935,0.000414451,0.0002289466,0.0005848196,0.0005311972,0.0007461516,0.002375398],"category_scores_gemma":[0.0006209521,0.0004196289,0.0007810605,0.0003439226,0.000514266,0.0006572003,0.0002345467,0.001748439,0.000500385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008501687,"about_ca_system_score_gemma":0.000622785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001105817,"about_ca_topic_score_gemma":0.004331541,"domain_scores_codex":[0.999658,0.0001850256,0.00002213594,0.00004371782,0.00003054383,0.00006061369],"domain_scores_gemma":[0.9997185,0.00006019969,0.000052833,0.00001823023,0.00001360272,0.0001367214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.6276908,0.05196548,0.01178629,0.001773538,0.002525062,0.001048994,0.0003917139,0.003931878,0.06242371,0.0003920385,0.00462245,0.2314481],"study_design_scores_gemma":[0.3703761,0.5826818,0.02954554,0.0000958723,0.001087474,0.001129179,0.0001644107,0.002924951,0.006503707,0.0001834685,0.005265994,0.0000415246],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9949291,0.002722425,0.0001606948,0.000240034,0.00006985154,0.000503992,0.0002116695,0.00003465866,0.001127566],"genre_scores_gemma":[0.996152,0.001492639,0.000433158,0.0002404256,0.00008526326,0.0003754742,0.0003789605,0.000008952567,0.0008331554],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.002375398,"threshold_uncertainty_score":0.007946491,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04692795090637122,"score_gpt":0.392467603550437,"score_spread":0.3455396526440657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}