{"id":"W4410845417","doi":"10.1016/j.cllc.2025.05.006","title":"KRAS ctDNA Detection in Patients With Resectable Lung Adenocarcinoma","year":2025,"lang":"en","type":"article","venue":"Clinical Lung Cancer","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Fondation de l'Hôpital Général de Montréal; Fonds de Recherche du Québec - Santé; American Society on Aging; American Surgical Association Foundation","keywords":"Medicine; KRAS; Adenocarcinoma; Internal medicine; Stage (stratigraphy); Liquid biopsy; Oncology; Clinical trial; Biopsy; Gastroenterology; Cancer; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001442752,0.0001344866,0.0003214809,0.0001273531,0.00007737754,0.00001686505,0.00006370709,0.0001248037,0.000159114],"category_scores_gemma":[0.00008520332,0.0001000122,0.00007916276,0.0004581006,0.00006483668,0.00009130607,0.00002352673,0.0002934034,0.000007179375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005323446,"about_ca_system_score_gemma":0.0005014392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00036724,"about_ca_topic_score_gemma":0.001095167,"domain_scores_codex":[0.9987286,0.00005305548,0.0004029882,0.0003809377,0.0001836409,0.00025074],"domain_scores_gemma":[0.99924,0.0001290912,0.00007984874,0.0002912802,0.0001544313,0.0001053169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009532124,0.0003460088,0.9800365,0.0001032322,0.0002915447,0.000009074407,0.0000600235,0.00002264958,0.000005543518,0.00005871083,0.003126326,0.01498716],"study_design_scores_gemma":[0.007519467,0.0003591461,0.9879816,0.0004597326,0.000583688,4.220767e-7,0.00002205095,0.0004883747,0.0001034542,0.00005631084,0.002324152,0.0001015709],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874471,0.002712199,0.0002540431,0.0009556132,0.0007783106,0.001094862,0.00001757832,0.00005676923,0.006683503],"genre_scores_gemma":[0.9937891,0.0001374447,0.0001422526,0.0009006296,0.0001442025,0.0002388458,0.00002872308,0.00001914917,0.00459965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01488559,"threshold_uncertainty_score":0.4078378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307508835563993,"score_gpt":0.3976272195076861,"score_spread":0.3845521311520462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}