{"id":"W4410851856","doi":"10.1371/journal.pcbi.1011859","title":"Cellular morphodynamics as quantifiers for functional states of resident tissue macrophages in vivo","year":2025,"lang":"en","type":"article","venue":"PLoS Computational Biology","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"European Research Council; Deutsche Forschungsgemeinschaft","keywords":"In vivo; Population; Beach morphodynamics; Biology; Neuroscience; Phenotype; Cell; Cell biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002875265,0.0003143121,0.0002837397,0.0004769465,0.0001755407,0.0005543047,0.0003860704,0.0005085141,0.001066936],"category_scores_gemma":[0.000813019,0.0002664954,0.0004277863,0.0002700324,0.0004080513,0.0003431855,0.0003731635,0.0004516818,0.000129053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003663096,"about_ca_system_score_gemma":0.0004036749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001988094,"about_ca_topic_score_gemma":0.00229036,"domain_scores_codex":[0.999907,0.00001822853,0.000005049294,0.00002984417,0.00002382964,0.00001606788],"domain_scores_gemma":[0.999851,0.00006777947,0.00003298862,0.00001631175,0.00001626447,0.00001565933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003266773,0.0001452997,0.02693727,0.0004851368,0.0001365711,0.0002235797,0.0004465279,0.5392945,0.3754569,0.01375378,0.001357968,0.04143582],"study_design_scores_gemma":[0.00001400684,0.00005773886,0.01087609,0.00000980472,0.0000250858,0.00008372713,0.00006635,0.9675853,0.01605847,0.003628083,0.001568429,0.00002685662],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6266106,0.0004272695,0.3678157,0.0002340226,0.00004742601,0.00008925282,0.001422094,0.0008835515,0.002470122],"genre_scores_gemma":[0.9259621,0.0002886194,0.07194854,0.00007584151,0.00001869374,0.0001675636,0.0006277959,0.0001797489,0.0007311705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001988094,"threshold_uncertainty_score":0.003953099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01269830061815353,"score_gpt":0.276528024656706,"score_spread":0.2638297240385524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}