{"id":"W4410861500","doi":"10.31557/apjcp.2025.26.5.1529","title":"Efficacy and Safety of Lenvatinib versus Atezolizumab Plus Bevacizumab in the Treatment of Unresectable Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis","year":2025,"lang":"en","type":"review","venue":"Asian Pacific Journal of Cancer Prevention","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Universitas Udayana","keywords":"Atezolizumab; Lenvatinib; Medicine; Bevacizumab; Hepatocellular carcinoma; Oncology; Meta-analysis; Internal medicine; Cancer; Chemotherapy; Nivolumab; Sorafenib; Immunotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00125893,0.0004998359,0.008655763,0.0007431317,0.00005198974,0.00002134761,0.0001830754,0.0001986323,0.00008867736],"category_scores_gemma":[0.0001048632,0.00027318,0.00296143,0.001301988,0.00008562337,0.00008761124,0.0000254245,0.0002441342,5.060749e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004103735,"about_ca_system_score_gemma":0.0007637959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001083911,"about_ca_topic_score_gemma":0.00005023973,"domain_scores_codex":[0.9950742,0.001333603,0.002502151,0.0003364102,0.0005276965,0.0002259835],"domain_scores_gemma":[0.9960685,0.0005247396,0.0024955,0.0005762014,0.0002358998,0.00009913796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0006532913,0.0007254229,0.0007695884,0.8210691,0.1436587,0.0001491758,0.0008628691,5.071908e-7,3.847151e-7,0.0000419103,0.00002126506,0.03204776],"study_design_scores_gemma":[0.00446849,0.002026198,0.0000768368,0.05948705,0.9299109,0.0001155783,0.000238814,0.0000125437,0.000008274006,0.00001223117,0.003469487,0.0001736061],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000622217,0.9935955,0.00003102778,0.000176852,0.00004964209,0.005118561,0.0000958322,0.000003204541,0.0003071007],"genre_scores_gemma":[0.1080496,0.8910496,0.00007393309,0.00000424505,0.0000226983,0.0003567657,0.00007059377,0.00002042672,0.0003520899],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7862522,"threshold_uncertainty_score":0.999972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.116385889156416,"score_gpt":0.3616738043371305,"score_spread":0.2452879151807145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}