{"id":"W4410864673","doi":"10.3390/jcm14113802","title":"The Effect on Quality of Life of Therapeutic Plasmapheresis and Intravenous Immunoglobulins on a Population of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients with Elevated β-Adrenergic and M3-Muscarinic Receptor Antibodies—A Pilot Study","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Medicine","topic":"Fibromyalgia and Chronic Fatigue Syndrome Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Chronic fatigue syndrome; Plasmapheresis; Encephalomyelitis; Antibody; Population; Intravenous Immunoglobulins; Immunology; Internal medicine; Multiple sclerosis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004747502,0.0004301512,0.0005584953,0.0002214343,0.0004327878,0.0002925762,0.0001855809,0.0003987211,0.001276951],"category_scores_gemma":[0.0007987052,0.00008916004,0.0006296467,0.0001240762,0.0002620199,0.000235603,0.0002284293,0.0004893652,0.0001349363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003114506,"about_ca_system_score_gemma":0.0002428095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007187575,"about_ca_topic_score_gemma":0.0008421949,"domain_scores_codex":[0.9998025,0.0000816204,0.00001236466,0.00003434501,0.00001941635,0.00004968922],"domain_scores_gemma":[0.999501,0.000104538,0.00007179142,0.00002408953,0.0000332181,0.0002652487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3122016,0.08827033,0.4221189,0.0003629176,0.00171126,0.001372585,0.001071528,0.001093692,0.01310501,0.0001494895,0.001299444,0.1572433],"study_design_scores_gemma":[0.01438068,0.3063314,0.6747182,0.00003390328,0.0005364229,0.0007401387,0.0004045796,0.001029987,0.0007822572,0.00007764291,0.0009344695,0.00003035971],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995325,0.0001928296,0.00001683021,0.00002179018,0.000008106646,0.00002158142,0.0000253868,0.000001435315,0.0001797179],"genre_scores_gemma":[0.9996127,0.00009146221,0.00003768602,0.00002958611,0.0000231639,0.0000379846,0.00005906067,4.110175e-7,0.0001079541],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001276951,"threshold_uncertainty_score":0.004271805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04867551445557283,"score_gpt":0.3847929563254787,"score_spread":0.3361174418699058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}