{"id":"W4410904147","doi":"10.5267/j.ccl.2025.3.001","title":"Pharmacological profile of condensed heterocyclic compounds based on functionally substituted [1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles: A review","year":2025,"lang":"en","type":"review","venue":"Current Chemistry Letters","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Thiadiazoles; Chemistry; Stereochemistry; Combinatorial chemistry; Computational chemistry; Organic chemistry; Medicinal chemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002651463,0.0006445819,0.0009232092,0.001530395,0.0001786772,0.0005734116,0.0005441536,0.0004402702,0.002752454],"category_scores_gemma":[0.0002981676,0.0002590199,0.0003632533,0.001341457,0.0002116957,0.000658883,0.0002731406,0.000741638,0.001100883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003488045,"about_ca_system_score_gemma":0.0005496858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006553131,"about_ca_topic_score_gemma":0.001248128,"domain_scores_codex":[0.999921,0.00001010014,0.00001299122,0.00001976201,0.00002706761,0.000009111795],"domain_scores_gemma":[0.9998908,0.00004619346,0.00002154658,0.00000330129,0.0000293333,0.000008769018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001659403,0.0001747737,0.0002954284,0.03230514,0.0001465851,0.0003136026,0.00008493591,0.0007071471,0.01621884,0.003415172,0.01525798,0.9309146],"study_design_scores_gemma":[0.00004002179,0.0005914125,0.001817059,0.002627767,0.0002789053,0.001802631,0.00007804891,0.000271562,0.006071593,0.0009972213,0.985384,0.00003969777],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001006718,0.9968016,0.0002158373,0.0001264457,0.0001033936,0.00001101913,0.00006211958,0.00001064933,0.001662092],"genre_scores_gemma":[0.00286941,0.9957069,0.0002802931,0.0001323035,0.00007841716,0.0000116516,0.00007967681,0.000001992558,0.0008394548],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002752454,"threshold_uncertainty_score":0.009207845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06667128474029997,"score_gpt":0.3424037295402726,"score_spread":0.2757324447999726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}