{"id":"W4410906053","doi":"10.1101/2025.05.29.656831","title":"High-throughput screening reveals diverse lambdoid prophage inducers","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Prophage; Throughput; Inducer; Computational biology; Computer science; Biology; Genetics; Gene; Telecommunications","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005824796,0.000619036,0.000673343,0.0008226536,0.0002178095,0.0007530865,0.0003453559,0.0004560937,0.00111995],"category_scores_gemma":[0.0004829289,0.0002047084,0.0003946439,0.0006752293,0.0001859371,0.0002377563,0.0003711619,0.0005573104,0.0006575133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000307284,"about_ca_system_score_gemma":0.0002575586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004340852,"about_ca_topic_score_gemma":0.0008594614,"domain_scores_codex":[0.9995902,0.00008316597,0.00002673306,0.00007621062,0.0001792788,0.00004440216],"domain_scores_gemma":[0.9997092,0.0001255506,0.00003864962,0.00003409022,0.00004647261,0.00004607921],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002270682,0.0002329003,0.0009182778,0.0001547778,0.00002635777,0.00008172428,0.00002251363,0.0007916726,0.9890791,0.00006164943,0.0001919103,0.008211999],"study_design_scores_gemma":[0.00005924343,0.002144631,0.005593142,0.00002133795,0.00005683796,0.0002170273,0.00004699189,0.002478056,0.9860812,0.00008567581,0.003197385,0.00001834401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773049,0.004864478,0.009213228,0.0003594117,0.0000306785,0.0003749748,0.003430784,0.0006768576,0.003744697],"genre_scores_gemma":[0.9739386,0.003909281,0.01293577,0.0001435902,0.00002305855,0.0001874718,0.004916428,0.0001129314,0.00383288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00111995,"threshold_uncertainty_score":0.003746569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01215561612338061,"score_gpt":0.2309846569927541,"score_spread":0.2188290408693734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}