{"id":"W4410940578","doi":"10.1021/acssuschemeng.5c01218","title":"Toward Clickable Protein Networks: Orthogonal Amidation of Self-Assembled Lysozyme and Bovine Serum Albumin Nanofibers","year":2025,"lang":"en","type":"article","venue":"ACS Sustainable Chemistry & Engineering","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Lysozyme; Bovine serum albumin; Nanofiber; Chemistry; Biophysics; Polymer chemistry; Biochemistry; Nanotechnology; Materials science; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002069014,0.0002176284,0.0002665851,0.00003986296,0.00005764832,0.00003594382,0.0001714473,0.0001827083,0.00001677289],"category_scores_gemma":[0.0001247434,0.0002312109,0.00009880767,0.0002981563,0.00001961246,0.00001172285,0.0002072734,0.0001049055,2.509821e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006087201,"about_ca_system_score_gemma":0.00008693003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001984105,"about_ca_topic_score_gemma":4.131597e-7,"domain_scores_codex":[0.998809,0.00001233849,0.0003067275,0.000371663,0.0001079894,0.0003923069],"domain_scores_gemma":[0.9993761,0.00002041931,0.00009052667,0.0002860544,0.000143209,0.00008375844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003070546,0.00004444708,0.0005069854,0.0007286514,0.0001691774,0.000006103922,0.00001217597,0.002318784,0.9955752,0.0002125302,0.0001227125,0.0002725372],"study_design_scores_gemma":[0.0003454795,0.00002432512,0.0001703234,0.00006681003,0.0000731078,0.000003486225,0.0001634611,0.003243423,0.9867453,0.0000236273,0.008923887,0.0002167497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934793,0.001069187,0.004519361,0.0001644142,0.00001418207,0.0001495397,0.000002986208,0.00003851273,0.000562583],"genre_scores_gemma":[0.9961051,0.0001174976,0.0007893344,0.00002156245,0.00008594873,0.00004619213,0.00005639338,0.00002270544,0.002755235],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008829869,"threshold_uncertainty_score":0.9428505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002109947655489494,"score_gpt":0.1842073745231341,"score_spread":0.1820974268676446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}