{"id":"W4410942673","doi":"10.3390/v17060802","title":"Progress in Pseudotyping Lentiviral Vectors Towards Cell-Specific Gene Delivery In Vivo","year":2025,"lang":"en","type":"review","venue":"Viruses","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Genetic enhancement; Ex vivo; Gene delivery; Viral vector; Tropism; Cell therapy; Biology; In vivo; Computational biology; Transgene; Cell biology; Stem cell; Gene; Immunology; Virus; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004577583,0.0005297864,0.0009956992,0.0006484232,0.00005500752,0.00007013985,0.0007280878,0.0005586269,0.00007940733],"category_scores_gemma":[0.00002945331,0.0005050299,0.0003513607,0.0007271359,0.0001310824,0.000008299315,0.0003940149,0.000461122,0.00004050295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001873791,"about_ca_system_score_gemma":0.0009443528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005955357,"about_ca_topic_score_gemma":0.0003382271,"domain_scores_codex":[0.9970533,0.0004898469,0.000644075,0.0008967402,0.000271493,0.0006445942],"domain_scores_gemma":[0.9989323,0.0000448176,0.0001619996,0.0007258469,0.00005612783,0.00007888811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005985569,0.0003972929,0.0005340652,0.007026464,0.000152448,0.0001215908,0.00004102211,0.00001008331,0.01199257,0.000007499177,0.004071789,0.9750466],"study_design_scores_gemma":[0.0005634003,0.000477539,0.00002796876,0.003368011,0.00004284076,0.000004811486,0.00001197367,0.000001398975,0.06452318,0.000005223381,0.9303781,0.0005954843],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0345221,0.9638354,0.000004377428,0.000006571127,0.0002554952,0.000872637,0.0001384785,0.00002035249,0.0003445982],"genre_scores_gemma":[0.001869082,0.9967477,0.00009059173,0.00007787086,0.0002572172,0.0003447693,0.0001403958,0.00008461431,0.0003877861],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9744511,"threshold_uncertainty_score":0.9997401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0489247756290354,"score_gpt":0.3525178380594529,"score_spread":0.3035930624304174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}