{"id":"W4410942673","doi":"10.3390/v17060802","title":"Progress in Pseudotyping Lentiviral Vectors Towards Cell-Specific Gene Delivery In Vivo","year":2025,"lang":"en","type":"review","venue":"Viruses","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Genetic enhancement; Ex vivo; Gene delivery; Viral vector; Tropism; Cell therapy; Biology; In vivo; Computational biology; Transgene; Cell biology; Stem cell; Gene; Immunology; Virus; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001191836,0.000740094,0.0006593151,0.0008565566,0.0002052193,0.001256134,0.0005944233,0.0006260283,0.001282796],"category_scores_gemma":[0.0006214772,0.0003711428,0.0005881893,0.0005611072,0.0005665148,0.00102849,0.000540483,0.001754826,0.001234069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004127501,"about_ca_system_score_gemma":0.000587555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004244193,"about_ca_topic_score_gemma":0.0003460437,"domain_scores_codex":[0.9992934,0.0001614765,0.00009104414,0.0001149379,0.0002937095,0.00004531],"domain_scores_gemma":[0.9997618,0.0000883242,0.00004622408,0.00002679897,0.00005817848,0.00001874588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000128153,0.000123468,0.0004954097,0.004277314,0.00006793275,0.0004265387,0.000319317,0.001382837,0.7406536,0.01801281,0.002919943,0.2311928],"study_design_scores_gemma":[0.00006232227,0.0008721268,0.001252639,0.0006550474,0.0001737091,0.002901582,0.00008846645,0.002817489,0.4716372,0.003782687,0.515646,0.0001108611],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07283846,0.611095,0.2816321,0.0014657,0.00162229,0.0007119701,0.0007170911,0.001601572,0.02831591],"genre_scores_gemma":[0.1599203,0.6448749,0.1772501,0.001821378,0.0006057266,0.0007308967,0.00223105,0.0005033839,0.01206225],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001282796,"threshold_uncertainty_score":0.006303132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0489247756290354,"score_gpt":0.3525178380594529,"score_spread":0.3035930624304174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}