{"id":"W4410943999","doi":"10.1056/nejmoa2502931","title":"Overall Survival with Neoadjuvant Nivolumab plus Chemotherapy in Lung Cancer","year":2025,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":160,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; McGill University Health Centre","funders":"Bristol-Myers Squibb","keywords":"Nivolumab; Medicine; Oncology; Chemotherapy; Neoadjuvant therapy; Internal medicine; Lung cancer; Cancer; Immunotherapy; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001653297,0.0002901431,0.0006679447,0.0001876247,0.0001408013,0.0003477373,0.0002034904,0.0002744029,0.0008658779],"category_scores_gemma":[0.002053697,0.0001126265,0.0007455141,0.0001605899,0.0003003588,0.000416056,0.0002793811,0.0006373239,0.00009721973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006552241,"about_ca_system_score_gemma":0.0005961765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000320745,"about_ca_topic_score_gemma":0.001030416,"domain_scores_codex":[0.9993929,0.0003656038,0.00003373418,0.00007894176,0.00007153401,0.00005743618],"domain_scores_gemma":[0.9990565,0.0004339281,0.0002606305,0.00005516413,0.00004217388,0.0001516939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3803195,0.005216818,0.1591681,0.001435771,0.003004702,0.0001937701,0.0001786199,0.01461162,0.02035495,0.000418785,0.003173408,0.4119239],"study_design_scores_gemma":[0.04299241,0.3403802,0.5646356,0.0005998656,0.005224934,0.001366541,0.0001595051,0.01877441,0.01148804,0.002662331,0.01162689,0.00008923046],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899706,0.008029999,0.0004673345,0.0003336877,0.00007413913,0.00005836382,0.0001140024,0.0000202563,0.0009315793],"genre_scores_gemma":[0.998329,0.0009100843,0.000237228,0.0001233604,0.00004306151,0.00006323918,0.0001755868,0.000003036963,0.0001153081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001653297,"threshold_uncertainty_score":0.008743584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01091992738661193,"score_gpt":0.2999416408862375,"score_spread":0.2890217134996256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}