{"id":"W4410951360","doi":"10.3390/biom15060797","title":"Tuning Autophagy for Improved Liver Transplant Outcomes: Insights from Experimental Models","year":2025,"lang":"en","type":"review","venue":"Biomolecules","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"BC Children's Hospital","keywords":"Autophagy; Economic shortage; Liver transplantation; Xenotransplantation; Immune modulation; Intensive care medicine; Medicine; Organ transplantation; Scarcity; Reperfusion injury; Transplantation; Immune system; Immunology; Biology; Ischemia; Surgery; Internal medicine; Economics; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00003528074,0.0005993827,0.001869097,0.0002422842,0.0000999163,0.00003509073,0.0002619451,0.0004202347,0.00007007342],"category_scores_gemma":[0.00001313251,0.0004315407,0.001176878,0.000147671,0.00008789727,0.00006771254,0.00004593114,0.0001725386,0.00002020344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001249266,"about_ca_system_score_gemma":0.0004932378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000813541,"about_ca_topic_score_gemma":0.000003185296,"domain_scores_codex":[0.9982563,0.00007003978,0.0005692326,0.0006306611,0.0001676445,0.0003060867],"domain_scores_gemma":[0.9988534,0.0002159896,0.0001806716,0.000522918,0.00004387997,0.0001830737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004051888,0.001362116,7.643849e-7,0.0249413,0.005375567,0.0006832231,0.001001646,4.171699e-7,0.00365763,0.005843522,0.0008469789,0.9558817],"study_design_scores_gemma":[0.005483974,0.0005651258,0.000006877189,0.03767265,0.007945934,0.00003927818,0.0001129111,0.002638815,0.009043316,0.001105998,0.9339044,0.001480694],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000921628,0.9889981,0.007038913,0.00002010621,0.0003577551,0.002005959,0.0009123575,0.0001567615,0.0004179409],"genre_scores_gemma":[0.0008262351,0.9933334,0.00158405,0.0004734085,0.0001808395,0.0006228814,0.00206078,0.00008814865,0.0008302596],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.954401,"threshold_uncertainty_score":0.9998136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05274994022126239,"score_gpt":0.3544711850511601,"score_spread":0.3017212448298977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}