{"id":"W4410951360","doi":"10.3390/biom15060797","title":"Tuning Autophagy for Improved Liver Transplant Outcomes: Insights from Experimental Models","year":2025,"lang":"en","type":"review","venue":"Biomolecules","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"BC Children's Hospital","keywords":"Autophagy; Economic shortage; Liver transplantation; Xenotransplantation; Immune modulation; Intensive care medicine; Medicine; Organ transplantation; Scarcity; Reperfusion injury; Transplantation; Immune system; Immunology; Biology; Ischemia; Surgery; Internal medicine; Economics; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007876892,0.0008524359,0.001426897,0.001989593,0.000205987,0.001068503,0.0005588359,0.0008792773,0.002258654],"category_scores_gemma":[0.0005993336,0.0002207732,0.0005940226,0.001191912,0.0004838749,0.001110168,0.0006525823,0.001574088,0.001296896],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004644645,"about_ca_system_score_gemma":0.0006064432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003704735,"about_ca_topic_score_gemma":0.0007929074,"domain_scores_codex":[0.9998428,0.0000291292,0.00002636198,0.00003606604,0.00005084493,0.0000147638],"domain_scores_gemma":[0.9997198,0.0001516176,0.00003308959,0.00001234552,0.00006191165,0.00002129582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001550087,0.0001512807,0.0002288751,0.02880679,0.0001658735,0.0002176693,0.00008299085,0.0005527911,0.01181325,0.009138219,0.01373958,0.9349477],"study_design_scores_gemma":[0.00002815796,0.0003292607,0.001229384,0.005788728,0.0002660787,0.001250768,0.00008079614,0.000201684,0.00461451,0.005092036,0.9810754,0.0000431268],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002752175,0.9981152,0.0002545727,0.0002166285,0.00008868888,0.000005880261,0.00002748664,0.00001107517,0.001005312],"genre_scores_gemma":[0.001383757,0.9976787,0.0003168581,0.0001543032,0.00007301518,0.000008398839,0.00003758155,0.000002580791,0.0003447618],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002258654,"threshold_uncertainty_score":0.007555962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05274994022126239,"score_gpt":0.3544711850511601,"score_spread":0.3017212448298977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}