{"id":"W4410956672","doi":"10.1038/s41577-025-01194-x","title":"Fetal Treg cell reprogramming links maternal immunity to neurodevelopment","year":2025,"lang":"en","type":"review","venue":"Nature reviews. Immunology","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Disability Prevention and Rehabilitation; University of Toronto","funders":"","keywords":"Reprogramming; Treg cell; Fetus; Immunity; Immunology; Biology; Medicine; Neuroscience; Cell; Immune system; Pregnancy; T cell; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007017165,0.0009948512,0.001149324,0.001118564,0.0002273547,0.001149697,0.001065991,0.001428459,0.004354434],"category_scores_gemma":[0.0008451383,0.0002639395,0.0003351615,0.001039456,0.0006609594,0.001152828,0.001098162,0.002399546,0.00277214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007141318,"about_ca_system_score_gemma":0.0008303457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005395113,"about_ca_topic_score_gemma":0.001138515,"domain_scores_codex":[0.9998467,0.00002727257,0.00001660267,0.00002728469,0.00005882157,0.00002329041],"domain_scores_gemma":[0.9995883,0.0001949918,0.00004490298,0.00001650684,0.00009503144,0.00006014193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001095908,0.00003081532,0.000136269,0.00536215,0.00004443619,0.0001883377,0.00002369277,0.0002867885,0.002426983,0.005888931,0.08969606,0.8958058],"study_design_scores_gemma":[0.00001790009,0.00005565612,0.0007279388,0.002189085,0.00004948723,0.0008661635,0.00003227737,0.00007991325,0.0004650973,0.003495971,0.9920056,0.00001478156],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007868235,0.9965298,0.0001933541,0.0008175053,0.00111869,0.000002739034,0.00002504724,0.00001293521,0.001221379],"genre_scores_gemma":[0.0005677433,0.9970486,0.0001147609,0.0004344344,0.0008054751,0.000005624458,0.00003814748,0.000002342879,0.0009829316],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004354434,"threshold_uncertainty_score":0.01456708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02171322035821476,"score_gpt":0.3166097137085398,"score_spread":0.294896493350325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}