{"id":"W4410969679","doi":"10.1093/pnasnexus/pgaf179","title":"One-hour postload glucose levels predict mortality from cardiovascular diseases and malignant neoplasms in healthy subjects","year":2025,"lang":"en","type":"article","venue":"PNAS Nexus","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Moonshot Research and Development Program; Pfizer Japan; Japan Science and Technology Agency; Keio University; Astellas Pharma; Ministry of Education, Culture, Sports, Science and Technology; Daiichi Sankyo Europe; Culture.lu; Ministry of Health; Takeda Pharmaceutical Company; Ministry of Higher Education and Scientific Research; Japan Society for the Promotion of Science; Mochida Memorial Foundation for Medical and Pharmaceutical Research; Health Sciences Centre Foundation; Takeda Science Foundation; Bayer Yakuhin; Daiichi-Sankyo; Japan Agency for Medical Research and Development; Pfizer","keywords":"Internal medicine; Concordance; Population; Cohort; Medicine; Mortality rate","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006206062,0.0003730754,0.0003504775,0.0007691152,0.000260204,0.0005886705,0.0002399064,0.0005140868,0.0008446589],"category_scores_gemma":[0.001218106,0.0002825875,0.0003088615,0.0007261193,0.0002295684,0.0003377097,0.0002666146,0.0004552695,0.00024398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000124953,"about_ca_system_score_gemma":0.0001333085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002242937,"about_ca_topic_score_gemma":0.0019581,"domain_scores_codex":[0.9998129,0.00005256969,0.00001889113,0.00005016139,0.00003160521,0.00003394539],"domain_scores_gemma":[0.9991509,0.0002254519,0.0003052934,0.00008591337,0.00006906027,0.0001634305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002668439,0.00002107036,0.9987675,0.00000507078,0.00004276058,0.00002700492,0.00001390717,0.0000256409,0.0003065499,0.000004516785,0.00002405735,0.0004951535],"study_design_scores_gemma":[0.000004653279,0.00006663871,0.9996228,0.000001517644,0.00001817797,0.00004056207,0.0000287323,0.0001150764,0.00005558567,0.00001549143,0.00002931554,0.000001410556],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991373,0.000339955,0.00008616312,0.00001555702,0.000008276074,0.000003223181,0.0002267592,0.000003482395,0.0001793765],"genre_scores_gemma":[0.9994571,0.00008677371,0.00007633284,0.00001380405,0.00001362946,0.000003236026,0.0002648781,0.00000154981,0.00008278466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002242937,"threshold_uncertainty_score":0.004459739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01633752901055369,"score_gpt":0.2613146141311281,"score_spread":0.2449770851205744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}