{"id":"W4410973309","doi":"10.1111/imcb.70037","title":"Highlights of 2024: unleashing the power of NK cells—cancer's worst nightmare","year":2025,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Children's Hospital Foundation; PA Research Foundation; University of Queensland; National Breast Cancer Foundation; Canadian Institutes of Health Research; Tour de Cure; Cancer Research Society","keywords":"Cytotoxicity; CRISPR; Cancer cell; Cytokine; Cell; Cancer research; Cancer; Biology; Immunology; Gene; In vitro; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002698067,0.0008483014,0.0005179872,0.0006609735,0.001836526,0.004226098,0.00100385,0.003983431,0.0151898],"category_scores_gemma":[0.002812846,0.0002465669,0.0007147663,0.0004345257,0.001750301,0.003295001,0.002141494,0.006975967,0.004900953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002104668,"about_ca_system_score_gemma":0.003146732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002535034,"about_ca_topic_score_gemma":0.005919904,"domain_scores_codex":[0.9989507,0.0001964959,0.0000540053,0.0001405718,0.0004143873,0.0002436926],"domain_scores_gemma":[0.9978757,0.0004386243,0.00007999183,0.00007359066,0.000474524,0.001057674],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001654253,0.00004172208,0.0002664833,0.000254884,0.00001465466,0.00028115,0.0001260658,0.0001109743,0.002131126,0.00974396,0.8873454,0.09951814],"study_design_scores_gemma":[0.00001250841,0.00008920386,0.0002173158,0.0001156771,0.000009382848,0.0004246062,0.0001724845,0.00008822195,0.00105986,0.002956214,0.9948394,0.00001527047],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.004522022,0.3073018,0.004813695,0.4054959,0.2228092,0.00007546132,0.0004708048,0.0004743899,0.05403678],"genre_scores_gemma":[0.05182621,0.2390218,0.005912988,0.2469753,0.1699179,0.0001299615,0.0008816082,0.0004988341,0.2848354],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.0151898,"threshold_uncertainty_score":0.05081493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01040844026320787,"score_gpt":0.2865569120717077,"score_spread":0.2761484718084999,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}