{"id":"W4410992159","doi":"10.31219/osf.io/yj5fb_v1","title":"Mid-term neurocognitive outcomes after CAR T cell therapy in central nervous system lymphomas: statistical analysis plan","year":2025,"lang":"en","type":"preprint","venue":"","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Neurocognitive; Term (time); Central nervous system; CAR T-cell therapy; Statistical analysis; Plan (archaeology); Neuroscience; Medicine; T cell; Psychology; Cognition; Immunology; Biology; Immune system; Statistics; Mathematics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.05799467,0.001034329,0.002122621,0.003894229,0.0005588865,0.00162989,0.002339368,0.001324044,0.006605439],"category_scores_gemma":[0.07099783,0.0003120637,0.007313595,0.00277764,0.001345183,0.001480418,0.002170881,0.002193335,0.0006636218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00148941,"about_ca_system_score_gemma":0.002230545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002021833,"about_ca_topic_score_gemma":0.001039624,"domain_scores_codex":[0.9684818,0.01987049,0.002434775,0.00418393,0.003790228,0.001238869],"domain_scores_gemma":[0.9219025,0.05887529,0.00622483,0.008640697,0.003111434,0.001245143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01808435,0.001145952,0.7756481,0.001672912,0.02039136,0.0005090621,0.00059246,0.02272784,0.001296227,0.004648739,0.01737656,0.1359065],"study_design_scores_gemma":[0.0009878163,0.01223258,0.6988657,0.0006425073,0.007525166,0.0007575616,0.001063618,0.2419824,0.003352136,0.01346134,0.01889817,0.0002309896],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.7146524,0.00514178,0.2305517,0.002724872,0.0007728147,0.008137434,0.03290016,0.00154401,0.003574889],"genre_scores_gemma":[0.9288775,0.0004023531,0.03911791,0.0004070447,0.0001785147,0.01286903,0.01617707,0.0001772515,0.001793448],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.05799467,"threshold_uncertainty_score":0.3067088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02619972986616645,"score_gpt":0.3192107432866936,"score_spread":0.2930110134205272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}