{"id":"W4411017159","doi":"10.1200/go-24-00441","title":"Global Access to Multiple Myeloma Therapies","year":2025,"lang":"en","type":"article","venue":"JCO Global Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Multiple myeloma; Expanded access; Family medicine; Chimeric antigen receptor; Oncology; Internal medicine; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002899847,0.0002092823,0.0005423696,0.0001030732,0.00009507009,0.00006153427,0.0004937134,0.0002803116,0.001975774],"category_scores_gemma":[0.0003402859,0.0001814999,0.0001578519,0.001264696,0.0001626705,0.00008246539,0.0004314402,0.0001864402,0.0002927147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002057761,"about_ca_system_score_gemma":0.0008927905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006710452,"about_ca_topic_score_gemma":0.002250818,"domain_scores_codex":[0.9981089,0.0001487054,0.0003188793,0.0004681347,0.0003416504,0.000613781],"domain_scores_gemma":[0.9987412,0.0001765551,0.00004894926,0.0005110049,0.0002353352,0.0002869181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003394442,0.0004919202,0.3744142,0.00004885419,0.0003486127,0.0002570662,0.00009750674,0.00001751914,0.004769307,0.003876072,0.112956,0.4993285],"study_design_scores_gemma":[0.002471492,0.0007309269,0.369409,0.00002939057,0.00003853833,0.00006697431,0.0001167366,0.00005560992,0.0004416465,0.001234211,0.625298,0.000107581],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6229236,0.0007176028,0.0006832769,0.03468964,0.001106287,0.001210996,0.00006781301,0.0001916373,0.3384092],"genre_scores_gemma":[0.9706599,0.0001006001,0.001317851,0.01759638,0.0003555971,0.0001319072,0.00002017543,0.00001396203,0.00980362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5123419,"threshold_uncertainty_score":0.9989365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04368081239765278,"score_gpt":0.4343898033175966,"score_spread":0.3907089909199438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}