{"id":"W4411025725","doi":"10.1200/jco.2025.43.17_suppl.lba5","title":"Event-free survival (EFS) in MATTERHORN: A randomized, phase 3 study of durvalumab plus 5-fluorouracil, leucovorin, oxaliplatin and docetaxel chemotherapy (FLOT) in resectable gastric/gastroesophageal junction cancer (GC/GEJC).","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Gastric Cancer Management and Outcomes","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Docetaxel; Medicine; Oxaliplatin; Fluorouracil; Cancer; Chemotherapy; Internal medicine; Durvalumab; Gastroesophageal Junction; Oncology; Phases of clinical research; Adenocarcinoma; Colorectal cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008122861,0.0002483823,0.003390368,0.0007158305,0.00003506837,0.0000185045,0.0002805994,0.0002341073,0.0002042301],"category_scores_gemma":[0.002566205,0.0001903261,0.0003732802,0.0006963956,0.0001762471,0.000196076,0.0001573868,0.001097056,0.000001182258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005131137,"about_ca_system_score_gemma":0.001166992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001477352,"about_ca_topic_score_gemma":0.002472193,"domain_scores_codex":[0.9937246,0.00118357,0.003789814,0.0003449977,0.0005847281,0.0003723048],"domain_scores_gemma":[0.9953788,0.002128121,0.001707752,0.0003294724,0.0002853638,0.000170491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2964405,0.005279976,0.6217734,0.0001484351,0.00085131,0.0005621102,0.0004962804,0.0004106386,0.00005544131,0.00004364037,0.003814246,0.07012407],"study_design_scores_gemma":[0.5886291,0.007597757,0.3996212,0.0002483817,0.0005775614,0.00003763356,0.001166766,0.0008955126,0.00001743268,0.0002569023,0.0008555201,0.00009622418],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890558,0.0009547698,0.0006100701,0.005744824,0.001647563,0.001235084,0.000003401022,0.000008854513,0.0007395927],"genre_scores_gemma":[0.9951203,0.001658813,0.0007129914,0.0008398706,0.0005119383,0.0000487941,0.000002155868,0.00001842076,0.001086736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2921886,"threshold_uncertainty_score":0.7761273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06781187243049028,"score_gpt":0.4583103592518422,"score_spread":0.3904984868213519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}