{"id":"W4411046273","doi":"10.1016/j.stem.2025.05.008","title":"Hallmarks of MSCs: Key quality attributes for pharmacology and clinical use","year":2025,"lang":"en","type":"review","venue":"Cell stem cell","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Rehabilitation Institute; University Health Network","funders":"","keywords":"Biology; Key (lock); Quality (philosophy); Pharmacology; Computational biology; Biotechnology; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00110513,0.0009183511,0.001523418,0.002035664,0.0002124579,0.00165854,0.0009948555,0.001067571,0.003115223],"category_scores_gemma":[0.00135109,0.0002168866,0.0005061195,0.001684797,0.0007296323,0.001299448,0.000885456,0.002601067,0.00212496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006942221,"about_ca_system_score_gemma":0.001442246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009217568,"about_ca_topic_score_gemma":0.001468909,"domain_scores_codex":[0.9996587,0.00005438191,0.00005234887,0.00004605158,0.0001585361,0.00003003074],"domain_scores_gemma":[0.9992994,0.0003499515,0.00009108472,0.00001911406,0.0001829715,0.00005745096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008142109,0.00005429424,0.0001607625,0.009841966,0.00004491982,0.00009865774,0.00003298188,0.0002259248,0.003165076,0.006022226,0.02021021,0.9600616],"study_design_scores_gemma":[0.00002039378,0.00008963084,0.0004929264,0.002488035,0.00009360055,0.0005260078,0.00004624332,0.00007789929,0.001558059,0.002503381,0.9920834,0.00002038139],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001383105,0.9970413,0.0004347178,0.0006169636,0.0003555995,0.0000101412,0.00005394733,0.00001577801,0.001333283],"genre_scores_gemma":[0.0009937533,0.9969234,0.0005214107,0.0004229711,0.0002708947,0.00001126463,0.00009516918,0.000002840947,0.0007582789],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003115223,"threshold_uncertainty_score":0.01042151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2586948211858321,"score_gpt":0.5036270450324262,"score_spread":0.244932223846594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}