{"id":"W4411081559","doi":"10.1139/bcb-2024-0260","title":"MCPIP1 deficiency alleviates abdominal aortic aneurysm formation by inhibiting MAPK signaling","year":2025,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Aortic aneurysm repair treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Science Foundation of Shandong Province; National Natural Science Foundation of China","keywords":"Abdominal aortic aneurysm; MAPK/ERK pathway; Signal transduction; Aortic aneurysm; Aneurysm; Cell biology; Medicine; Internal medicine; Cardiology; Chemistry; Biology; Cancer research; Surgery","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000126372,0.000656162,0.0004461716,0.0003780285,0.0002456619,0.0002685576,0.0003047577,0.0003706285,0.001746278],"category_scores_gemma":[0.00009485717,0.0001756436,0.0003362505,0.000162045,0.0003054765,0.0002741184,0.0002336771,0.001351645,0.0003341486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002834699,"about_ca_system_score_gemma":0.0003596921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005126203,"about_ca_topic_score_gemma":0.0009167464,"domain_scores_codex":[0.9998312,0.00002038203,0.00001626858,0.0000306545,0.00003533946,0.00006625612],"domain_scores_gemma":[0.9998941,0.000008501408,0.00002976829,0.000006991294,0.00001157651,0.00004893669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006642416,0.0002029539,0.0002434887,0.0001604487,0.00001592122,0.00009637474,0.00002124671,0.00008450983,0.9941905,0.0001582346,0.0001832281,0.003978888],"study_design_scores_gemma":[0.000152239,0.001903823,0.007928575,0.00003226718,0.00009727356,0.0004209536,0.00008026374,0.0014452,0.9818527,0.0001617946,0.005908321,0.00001663298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98729,0.004094484,0.004585006,0.0004648306,0.0001883718,0.00009108204,0.0009861201,0.0003269244,0.001973106],"genre_scores_gemma":[0.9874592,0.002750969,0.004026904,0.0001834101,0.00005308097,0.0001330437,0.000842509,0.00004172059,0.004509158],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001746278,"threshold_uncertainty_score":0.005841851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007169061898657847,"score_gpt":0.2458630347329064,"score_spread":0.2386939728342485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}