{"id":"W4411085387","doi":"10.1093/intbio/zyaf009","title":"The creation and validation of a fully animal component-free media for select adherent cell types","year":2025,"lang":"en","type":"article","venue":"Integrative Biology","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; United Soybean Board","keywords":"Fetal bovine serum; Cell culture; In vitro; Biology; Chemically defined medium; Cell biology; Cell growth; Cell; Cell type; Transcriptome; Biotechnology; Andrology; Computational biology; Biochemistry; Gene expression; Genetics; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009208839,0.00008833345,0.0001013194,0.00002722127,0.0001018931,0.00001120063,0.000111305,0.00009377729,0.000006221139],"category_scores_gemma":[0.0003072544,0.00005391299,0.00005531016,0.00004618482,0.0001376847,0.000001990335,0.00006780389,0.00003823113,5.217327e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008036595,"about_ca_system_score_gemma":0.00004835827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003570107,"about_ca_topic_score_gemma":0.00008641357,"domain_scores_codex":[0.999469,0.00009207735,0.0001462319,0.0001701315,0.00002518087,0.00009732728],"domain_scores_gemma":[0.999447,0.0001253679,0.00008384851,0.0001455007,0.0001782169,0.00002003409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005199092,0.00004647191,0.003361502,0.00001539434,0.00005714384,4.003675e-8,0.00006837624,0.000003619396,0.9824896,0.003813004,0.007279981,0.002344966],"study_design_scores_gemma":[0.000548557,0.0009070186,0.002528477,0.00001592718,0.00002547187,5.912137e-7,0.000147142,0.0000672712,0.9753197,0.004797217,0.01557547,0.00006717863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907934,0.002355684,0.004814509,0.0002385276,0.0002259845,0.000283918,0.0000959406,0.000006403448,0.001185646],"genre_scores_gemma":[0.9989009,0.0002664632,0.0002245899,0.00006294704,0.00006695693,0.00008237018,0.00016324,0.000004352829,0.0002281945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008295488,"threshold_uncertainty_score":0.2198508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008064200102305423,"score_gpt":0.2885615798046064,"score_spread":0.280497379702301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}