{"id":"W4411085387","doi":"10.1093/intbio/zyaf009","title":"The creation and validation of a fully animal component-free media for select adherent cell types","year":2025,"lang":"en","type":"article","venue":"Integrative Biology","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; United Soybean Board","keywords":"Fetal bovine serum; Cell culture; In vitro; Biology; Chemically defined medium; Cell biology; Cell growth; Cell; Cell type; Transcriptome; Biotechnology; Andrology; Computational biology; Biochemistry; Gene expression; Genetics; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001776829,0.0006467733,0.000562001,0.0009947574,0.0006449887,0.001270408,0.0006970025,0.0008720452,0.0009313231],"category_scores_gemma":[0.001656135,0.0002426415,0.0007587073,0.0006477238,0.0005356567,0.0006579349,0.0007898043,0.0009976769,0.0008068102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000560104,"about_ca_system_score_gemma":0.0008996783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001510487,"about_ca_topic_score_gemma":0.00400153,"domain_scores_codex":[0.99866,0.0001945022,0.0001938238,0.0002371988,0.0006199746,0.00009453471],"domain_scores_gemma":[0.9986997,0.0003549396,0.0002311414,0.000153736,0.000479695,0.00008084322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006227281,0.00005502027,0.001181086,0.0003340177,0.00001843549,0.0001757609,0.0001081444,0.0002255517,0.9873804,0.0004821724,0.0004311998,0.009545972],"study_design_scores_gemma":[0.000008802551,0.0003295619,0.004647991,0.0001302721,0.00007847895,0.0004609685,0.0001494217,0.001050588,0.9671507,0.0001861945,0.02576583,0.00004112574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7541498,0.0193724,0.1964716,0.001428912,0.001020665,0.002120562,0.008984686,0.001027329,0.01542409],"genre_scores_gemma":[0.6776462,0.0142094,0.2761894,0.001195126,0.0001637854,0.00286497,0.01652127,0.0004401643,0.01076958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001776829,"threshold_uncertainty_score":0.009396911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008064200102305423,"score_gpt":0.2885615798046064,"score_spread":0.280497379702301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}