{"id":"W4411090765","doi":"10.1016/j.biomaterials.2025.123478","title":"Electrode stimulation parameter modifications elicit differential glial cell responses in vitro over a short 4-h timecourse","year":2025,"lang":"en","type":"article","venue":"Biomaterials","topic":"Neuroscience and Neural Engineering","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"Faculty of Medicine and Dentistry, University of Alberta; Canadian Institutes of Health Research; Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Alberta Health Services; U.S. Department of Defense","keywords":"Stimulation; Materials science; Electrode; Microglia; Microelectrode; Biomedical engineering; Biophysics; Neuromodulation; Neuroscience; Chemistry; Medicine; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001167581,0.0001665362,0.0001995518,0.0003336756,0.0001024339,0.0001489289,0.000245627,0.00007293604,0.00005425466],"category_scores_gemma":[0.0003195285,0.0001547225,0.00005416351,0.0004474934,0.00005804645,0.0002208853,0.00006335429,0.00002790879,0.00002764436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004840066,"about_ca_system_score_gemma":0.00004342685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001847258,"about_ca_topic_score_gemma":0.000001356287,"domain_scores_codex":[0.9985336,0.0001476642,0.0003324738,0.0004565176,0.0001840447,0.0003456855],"domain_scores_gemma":[0.9993746,0.0002426534,0.00004571323,0.0002778689,0.00001202411,0.0000471691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002826386,0.0000901528,0.0000518296,0.00001131504,8.37572e-7,0.000008384831,0.00002018753,0.00007261927,0.9990056,0.0001526149,0.00006112277,0.0002427697],"study_design_scores_gemma":[0.0002976776,0.00003349434,0.006726701,0.00001147449,0.000009018971,0.000002474619,0.000001427466,0.008291015,0.9841813,0.0001381147,0.000165183,0.0001420954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997875,0.000006699318,0.0005216157,0.0001146719,0.0008173269,0.0003370881,0.00005169705,0.0001249263,0.0001509465],"genre_scores_gemma":[0.999051,0.00001217387,0.00007541224,0.0002173232,0.00005958967,0.00005961953,0.000005700795,0.00001447419,0.0005047274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0148242,"threshold_uncertainty_score":0.63094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03442313004011722,"score_gpt":0.3097272867288268,"score_spread":0.2753041566887096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}