{"id":"W4411131186","doi":"10.1101/2025.06.07.658439","title":"Interprotomer Communication and Functional Asymmetry in H/ACA snoRNPs","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Asymmetry; Business; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000460133,0.0001349454,0.00007410874,0.0001353766,0.0002915012,0.0002466763,0.0001828875,0.0002056657,0.001062635],"category_scores_gemma":[0.0001050721,0.0001075475,0.000118528,0.0000677342,0.0002654916,0.0001999082,0.0001500231,0.0002821276,0.0002095236],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002192708,"about_ca_system_score_gemma":0.0001396762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007445311,"about_ca_topic_score_gemma":0.0007775909,"domain_scores_codex":[0.9999564,0.000003846329,0.000001971907,0.00001507996,0.00001344621,0.000009254253],"domain_scores_gemma":[0.9999146,0.0000147619,0.00003148246,0.000008953406,0.00001141151,0.0000186909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001360687,0.00001452466,0.001947212,0.0000299797,0.00001120941,0.0004525013,0.00007816053,0.001019599,0.9921967,0.001387632,0.0001275792,0.002598895],"study_design_scores_gemma":[0.00004005538,0.0002021079,0.0464648,0.00001732944,0.00003654907,0.002029012,0.0004265105,0.04600784,0.8947854,0.003314234,0.006642191,0.00003388179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938332,0.0002025375,0.004136538,0.0000414861,0.000008460359,0.000004119516,0.00005310501,0.00006399684,0.001656652],"genre_scores_gemma":[0.9983941,0.00003218237,0.00111449,0.00001137762,0.000002770176,0.000002850111,0.00005710092,0.000007978795,0.0003771856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001062635,"threshold_uncertainty_score":0.003554881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0208739319819317,"score_gpt":0.2787660361853837,"score_spread":0.257892104203452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}