{"id":"W4411149712","doi":"10.1053/j.gastro.2025.05.022","title":"Blood-Based T-Cell Diagnosis of Celiac Disease","year":2025,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Celiac Disease Research and Management","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Health and Medical Research Council; Coeliac Australia","keywords":"Gluten; Tetramer; Medicine; Immunology; Human leukocyte antigen; T cell; Internal medicine; Gastroenterology; Antigen; Chemistry; Immune system; Biochemistry; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006156145,0.0004722046,0.000399679,0.0008464186,0.0001390615,0.0004004324,0.0002230783,0.0003383349,0.001226912],"category_scores_gemma":[0.001109904,0.0001103633,0.0001229696,0.0002886799,0.0002301975,0.0001681659,0.0001857588,0.0003273845,0.0004369629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001241412,"about_ca_system_score_gemma":0.00007110214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005331544,"about_ca_topic_score_gemma":0.0005844579,"domain_scores_codex":[0.99958,0.0001420191,0.00005421193,0.00009437549,0.00009139983,0.00003801808],"domain_scores_gemma":[0.9993382,0.0002707973,0.000122403,0.00003861745,0.0001472417,0.00008273969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002198776,0.000151288,0.876625,0.0002589385,0.00006713334,0.0008464315,0.0001863057,0.0002796262,0.08171503,0.00005823263,0.0008721074,0.03674117],"study_design_scores_gemma":[0.0001434118,0.002689232,0.9093238,0.0001575625,0.0001755174,0.01283466,0.0002868506,0.003926896,0.06574789,0.0001787845,0.004505312,0.00003021461],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893671,0.00363906,0.003171496,0.00008688305,0.00005247127,0.00007697463,0.000554281,0.000116235,0.002935393],"genre_scores_gemma":[0.9953327,0.0004899245,0.003205003,0.0001099342,0.00004159638,0.00002432212,0.0003368233,0.000006468686,0.0004532459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001226912,"threshold_uncertainty_score":0.004104376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007023915421767886,"score_gpt":0.268200320748668,"score_spread":0.2611764053269001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}