{"id":"W4411149712","doi":"10.1053/j.gastro.2025.05.022","title":"Blood-Based T-Cell Diagnosis of Celiac Disease","year":2025,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Celiac Disease Research and Management","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Health and Medical Research Council; Coeliac Australia","keywords":"Gluten; Tetramer; Medicine; Immunology; Human leukocyte antigen; T cell; Internal medicine; Gastroenterology; Antigen; Chemistry; Immune system; Biochemistry; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001030262,0.000107765,0.0002448933,0.0002487439,0.00002488812,0.000004908655,0.0001096136,0.00002816028,0.0003233355],"category_scores_gemma":[0.00007804205,0.00009830906,0.0001632621,0.0001258236,0.0001183393,0.00001745769,0.00009897039,0.00009361914,0.00002091946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002385735,"about_ca_system_score_gemma":0.0001130273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002283763,"about_ca_topic_score_gemma":0.000009041666,"domain_scores_codex":[0.9989625,0.00006298743,0.0002099203,0.0002350043,0.0001756845,0.0003538999],"domain_scores_gemma":[0.9991855,0.00004211762,0.00004463937,0.0003763249,0.00007784591,0.0002735516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002448139,0.001816571,0.9698072,0.0007778289,0.0001556326,0.000224247,0.000004335039,0.00003118877,0.0007969802,0.0001831944,0.02276406,0.0009906172],"study_design_scores_gemma":[0.01351587,0.002285951,0.9386695,0.0002984032,0.001460616,0.000003134434,0.00004196498,0.000538293,0.00894018,0.0002421439,0.03389356,0.0001104007],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880503,0.0007740278,0.001066283,0.00731197,0.0001180008,0.0004919917,0.00004277272,0.00003773716,0.00210693],"genre_scores_gemma":[0.9958217,0.0002208795,0.0002497646,0.00251592,0.00002811598,0.0001684893,0.00005624657,0.000008950256,0.0009299158],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03113773,"threshold_uncertainty_score":0.4008927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007023915421767886,"score_gpt":0.268200320748668,"score_spread":0.2611764053269001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}