{"id":"W4411154570","doi":"10.1002/alz.70195","title":"Diverse tau pathologies in late‐life mood disorders revealed by PET and autopsy assays","year":2025,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Japan Science and Technology Agency; Japan Society for the Promotion of Science; Astellas Pharma; National Center of Neurology and Psychiatry; Astellas Foundation for Research on Metabolic Disorders; Japan Agency for Medical Research and Development","keywords":"Dementia; Positron emission tomography; Depression (economics); Mania; Mood disorders; Medicine; Autopsy; Neuropathology; Mood; Disease; Psychology; Pathology; Psychiatry; Internal medicine; Neuroscience; Bipolar disorder; Anxiety","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008058855,0.0004292193,0.0002140659,0.001419787,0.0003083757,0.0005161985,0.0002210506,0.0003570377,0.001283234],"category_scores_gemma":[0.001363531,0.0002274674,0.000193297,0.0003558567,0.0002518196,0.0002462258,0.0002605605,0.0001619437,0.0003673986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000208859,"about_ca_system_score_gemma":0.0001401106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000927628,"about_ca_topic_score_gemma":0.001345225,"domain_scores_codex":[0.9997922,0.00005450704,0.00003983837,0.00004806318,0.0000344535,0.00003099944],"domain_scores_gemma":[0.9994091,0.00009649446,0.0002542916,0.00004728659,0.000125283,0.00006756962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001097266,0.00008415012,0.9640079,0.00006611534,0.00007450695,0.005076262,0.000276418,0.00009443222,0.0219523,0.00006760813,0.0001472438,0.007055822],"study_design_scores_gemma":[0.00002928664,0.0005898021,0.9675675,0.00005150191,0.000101586,0.02259409,0.000284309,0.0004290314,0.007651755,0.0001844928,0.0005059174,0.00001071497],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969109,0.001231249,0.0004658662,0.00002166474,0.000006321054,0.00002259339,0.0001872935,0.00001418263,0.001139994],"genre_scores_gemma":[0.9987117,0.0003541592,0.0004878413,0.00002684972,0.000007866997,0.00001114538,0.0001923408,0.000001974309,0.0002062382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001419787,"threshold_uncertainty_score":0.004292846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.015756828735541,"score_gpt":0.2997493208352039,"score_spread":0.2839924920996629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}