{"id":"W4411181629","doi":"10.1128/jvi.00537-25","title":"Immunogenicity of NSDV GP38 and the role of furin in GP38 proteolytic processing","year":2025,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Viral Infections and Vectors","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"HORIZON EUROPE Framework Programme","keywords":"Immunogenicity; Biology; Furin; Computational biology; Biochemistry; Genetics; Antigen; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001354222,0.0002473425,0.0001395581,0.0001108692,0.000101153,0.0001783975,0.0001100518,0.0002429468,0.000521639],"category_scores_gemma":[0.0001700993,0.00006377597,0.0001673478,0.00006099471,0.0001715859,0.000140466,0.0000918313,0.0002704103,0.0001359602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002163086,"about_ca_system_score_gemma":0.00009944978,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006458231,"about_ca_topic_score_gemma":0.0003799173,"domain_scores_codex":[0.999928,0.00001645112,0.000006785051,0.00001104766,0.00001748462,0.00002015442],"domain_scores_gemma":[0.9998993,0.00002626329,0.00003230942,0.00001048328,0.00001710935,0.00001449971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000667839,0.00001264526,0.0004797388,0.00001940922,0.000001954652,0.00003412846,0.00001265265,0.00002214318,0.9990759,0.00001797034,0.000003723298,0.0002528502],"study_design_scores_gemma":[0.00001136142,0.000503971,0.04592987,0.00001228097,0.00001490843,0.0004200648,0.0000837862,0.001103371,0.9507632,0.00007785482,0.001075014,0.000004251152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989568,0.0004668483,0.0002722257,0.00002026768,0.000002306605,0.000005938159,0.00005017066,0.000002563501,0.0002229006],"genre_scores_gemma":[0.9987215,0.0002006943,0.0004963001,0.00001387016,0.000002882758,0.000006241871,0.0001681025,0.000001568486,0.0003887085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006458231,"threshold_uncertainty_score":0.001745045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003618201584870888,"score_gpt":0.2655851108487476,"score_spread":0.2619669092638767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}