{"id":"W4411192972","doi":"10.1093/gbe/evaf106","title":"Dynamic Birth and Death of Argonaute Gene Family Functional Repertoire Across <i>Caenorhabditis</i> Nematodes","year":2025,"lang":"en","type":"article","venue":"Genome Biology and Evolution","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Alliance de recherche numérique du Canada; University of Toronto; Innovation, Science and Economic Development Canada","keywords":"Biology; Repertoire; Argonaute; Caenorhabditis elegans; Gene; Genetics; Evolutionary biology; Caenorhabditis; Gene family; RNA interference; Genome; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001494889,0.0001118391,0.0001922983,0.0009130647,0.0002978392,0.0003293935,0.0001591098,0.0002236406,0.0004904007],"category_scores_gemma":[0.0003823896,0.0001114888,0.0001838116,0.0003559981,0.0003266942,0.0003297416,0.0003144652,0.0002534399,0.0001551736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001869449,"about_ca_system_score_gemma":0.0000992212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007557156,"about_ca_topic_score_gemma":0.001546372,"domain_scores_codex":[0.9998325,0.00001141903,0.00001471798,0.00007884036,0.00003163568,0.00003096116],"domain_scores_gemma":[0.999689,0.00007513625,0.000107125,0.00003407516,0.00004950687,0.00004522995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001829092,0.00001100357,0.1055285,0.00009809629,0.00004334682,0.0002280413,0.0004519956,0.0002078182,0.8828664,0.000186106,0.00007652369,0.01011929],"study_design_scores_gemma":[0.000002402983,0.00006973302,0.9666177,0.00001289955,0.00002984543,0.0009324464,0.0002519973,0.0005097348,0.02997049,0.0000960274,0.001491898,0.00001481166],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989364,0.0002564547,0.0002516919,0.000006663014,8.943421e-7,0.000002510743,0.0002020076,0.000008904431,0.0003345243],"genre_scores_gemma":[0.998399,0.0002087751,0.000550249,0.00002179205,0.000001842488,0.00001115258,0.0004221743,0.000006412335,0.0003786583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009130647,"threshold_uncertainty_score":0.001640558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006035635616407412,"score_gpt":0.2368850401474131,"score_spread":0.2308494045310057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}