{"id":"W4411197793","doi":"10.1016/s1470-2045(25)00194-9","title":"Partial-breast radiotherapy after breast conservation surgery for women with early breast cancer (UK IMPORT LOW): 10-year outcomes from a multicentre, open-label, randomised, controlled, phase 3, non-inferiority trial","year":2025,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Health Service Corps; Department of Health and Social Care; National Institute for Health and Care Research; Royal Marsden NHS Foundation Trust; Health and Care Research Wales; Institute of Cancer Research; Cancer Research UK; NIHR Cambridge Biomedical Research Centre; National Institute on Handicapped Research","keywords":"Medicine; Breast cancer; Open label; Breast-conserving surgery; Randomized controlled trial; Radiation therapy; Oncology; Surgery; Cancer; Internal medicine; Mastectomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003734609,0.000868842,0.002309994,0.0003200062,0.0003570413,0.001046008,0.0007445272,0.001265295,0.005394035],"category_scores_gemma":[0.00483139,0.0003884597,0.001800587,0.0004122961,0.0009622978,0.0009653346,0.0006662472,0.001792972,0.0005924648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009080656,"about_ca_system_score_gemma":0.0007992515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009429596,"about_ca_topic_score_gemma":0.002229152,"domain_scores_codex":[0.9980727,0.001469648,0.000106125,0.00013808,0.00008202963,0.0001313993],"domain_scores_gemma":[0.9974684,0.0008493605,0.0008963894,0.0002499684,0.0001553191,0.0003805646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9767506,0.003018797,0.001170973,0.001283117,0.000966923,0.00003632667,0.00005802495,0.0002921455,0.00114389,0.00006439642,0.001024785,0.01419013],"study_design_scores_gemma":[0.9166812,0.07622962,0.004416214,0.000141455,0.001166667,0.00004890662,0.00003095458,0.0002579358,0.0002002832,0.0001462255,0.0006639367,0.00001658688],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813443,0.01078372,0.0006582313,0.001041036,0.000375909,0.00227548,0.00128845,0.00008469306,0.002148181],"genre_scores_gemma":[0.9860991,0.003426014,0.001200316,0.001709171,0.0003139332,0.003627965,0.001646194,0.00002213206,0.001955134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005394035,"threshold_uncertainty_score":0.01975071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02365409318770184,"score_gpt":0.3391352122236972,"score_spread":0.3154811190359954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}