{"id":"W4411202328","doi":"10.1016/j.jaccas.2025.103683","title":"Hydroxychloroquine Cardiotoxicity and Sarcomeric Hypertrophic Cardiomyopathy","year":2025,"lang":"en","type":"article","venue":"JACC Case Reports","topic":"Drug-Induced Ocular Toxicity","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Alberta; University of Calgary","funders":"","keywords":"Cardiotoxicity; Hydroxychloroquine; Hypertrophic cardiomyopathy; Medicine; Cardiomyopathy; Internal medicine; Cardiology; Heart failure; Coronavirus disease 2019 (COVID-19); Chemotherapy; Disease; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002720262,0.0005667633,0.000406267,0.0009787141,0.0006813533,0.0005532787,0.0003339355,0.001584162,0.002184922],"category_scores_gemma":[0.001242608,0.0002469495,0.0003928804,0.0005875427,0.0007222232,0.0005613067,0.0005507586,0.000953614,0.0004964865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007232888,"about_ca_system_score_gemma":0.0004036697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001615996,"about_ca_topic_score_gemma":0.002294383,"domain_scores_codex":[0.9996704,0.00005010777,0.00003503929,0.00006215078,0.00007546366,0.0001069156],"domain_scores_gemma":[0.9987827,0.0003846454,0.0004603807,0.00007561038,0.00007949209,0.000217051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00007483793,0.00004059383,0.02629641,0.00007314762,0.00001335022,0.9664572,0.0001343242,0.00008115628,0.002766796,0.0002925852,0.0004865612,0.003282994],"study_design_scores_gemma":[0.00001455335,0.00008631754,0.01784245,0.00003866866,0.00002074292,0.9788143,0.00008815617,0.0002197286,0.0009777896,0.0001674589,0.001723193,0.000006636945],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9562247,0.01587132,0.00195313,0.002737964,0.0001968705,0.0001512981,0.000213884,0.0001459475,0.02250482],"genre_scores_gemma":[0.9965134,0.00155867,0.0002691366,0.0005418664,0.0001942982,0.00000740054,0.00005064475,0.000007464276,0.0008571549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002184922,"threshold_uncertainty_score":0.007309318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009675586961785457,"score_gpt":0.2689785274771987,"score_spread":0.2593029405154133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}