{"id":"W4411225300","doi":"10.1021/acsptsci.5c00206","title":"Olfactory Drug Delivery in Rodents: Deposition and Pharmacokinetics","year":2025,"lang":"en","type":"article","venue":"ACS Pharmacology & Translational Science","topic":"Olfactory and Sensory Function Studies","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; University of Victoria","funders":"","keywords":"Pharmacokinetics; Drug; Deposition (geology); Drug delivery; Pharmacology; Medicine; Nanotechnology; Biology; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003379929,0.000131727,0.0001291162,0.0003471721,0.0005104351,0.00003765023,0.0002278878,0.00003808347,0.0001004924],"category_scores_gemma":[0.0000457406,0.0001305033,0.00002564977,0.0008780039,0.0009195497,0.0005943614,0.0000577788,0.0002206448,0.00001569477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005960935,"about_ca_system_score_gemma":0.0001436184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009503258,"about_ca_topic_score_gemma":0.0000160106,"domain_scores_codex":[0.9984936,0.0001357075,0.000239958,0.0005028339,0.0003037888,0.0003241573],"domain_scores_gemma":[0.9993467,0.0003945244,0.00004691105,0.00006850845,0.00006908883,0.00007421057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000842358,0.00008520902,0.01413508,0.00001068862,0.000005276162,0.00001023124,0.000400251,0.0004691072,0.9810674,0.0008167004,0.0003430503,0.002572821],"study_design_scores_gemma":[0.001428581,0.00002165238,0.1414551,0.0000144283,0.00003883672,0.00001079397,0.00007613163,0.003268176,0.8490379,0.001001955,0.003461377,0.000184987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931083,0.0002977543,0.0002489249,0.002471779,0.001019944,0.0002243171,0.00001284143,0.00004871789,0.002567453],"genre_scores_gemma":[0.9955664,0.0002803451,0.0000787798,0.003778905,0.0000415935,0.00002000387,0.000001331033,0.00000407924,0.0002285404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1320294,"threshold_uncertainty_score":0.5321771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06440387562829268,"score_gpt":0.3170674049599366,"score_spread":0.2526635293316439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}