{"id":"W4411227238","doi":"10.1097/01.tp.0001123416.83809.ea","title":"P-11: TARGETING ISLET GRAFT-REGULATED NECROSIS USING NECROSTATIN-1-ELUTING MICROPARTICLES","year":2025,"lang":"en","type":"article","venue":"Transplantation","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Islet; Medicine; Necrosis; Diabetes mellitus; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001293708,0.0002785502,0.000148045,0.0001433449,0.00008485133,0.0002659061,0.000119811,0.000300226,0.0005554865],"category_scores_gemma":[0.00009529016,0.00008364116,0.0001843103,0.00007486158,0.0001435682,0.0002391367,0.0001698196,0.000307746,0.0002048437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002414396,"about_ca_system_score_gemma":0.0001400909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001734264,"about_ca_topic_score_gemma":0.0002237206,"domain_scores_codex":[0.9999354,0.000006876089,0.000005454072,0.00001969669,0.00001872231,0.00001379218],"domain_scores_gemma":[0.9999427,0.000008964764,0.00002639659,0.000003482601,0.000006969325,0.0000116772],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001272275,0.00006018048,0.000211763,0.0001003197,0.00000648096,0.0001245613,0.00001489355,0.0002928716,0.9947118,0.0000876876,0.00007425233,0.004187902],"study_design_scores_gemma":[0.00001795579,0.0005636049,0.001126509,0.000009699559,0.00001799127,0.0003071016,0.000009902362,0.001062359,0.9952813,0.00001949592,0.001579476,0.000004514277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877345,0.003330836,0.007214437,0.0001017863,0.00004303666,0.00006454484,0.000137809,0.0001080135,0.001264982],"genre_scores_gemma":[0.9879652,0.002430788,0.006896867,0.00006560186,0.00001760408,0.00006257415,0.0001733195,0.00001709572,0.002371054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005554865,"threshold_uncertainty_score":0.001858294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01090719849875696,"score_gpt":0.2634139481889607,"score_spread":0.2525067496902038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}